ATP as a multi-target danger signal in the brain

Por Rodrigues, Ricardo J., Tomé, Angelo R., Cunha, Rodrigo A.
Publicado no Front Neurosci (2015)

Functional distribution of Ca(2+)-coupled P2 purinergic receptors among adrenergic and noradrenergic bovine adrenal chromaffin cells

Por Tomé, Ângelo R, Castro, Enrique, Santos, Rosa M, Rosário, Luís M
Publicado em 2007

Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP

Por Tomé, Ângelo R, Castro, Enrique, Santos, Rosa M, Rosário, Luís M
Publicado em 2007

Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics

Por Barbosa, Rui M, Silva, Amélia M, Tomé, Angelo R, Stamford, Jonathan A, Santos, Rosa M, Rosário, Luís M
Publicado em 1998

Blockade of adenosine A(2A) receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Por Simões, Ana Patrícia, Duarte, João A, Agasse, Fabienne, Canas, Paula Margarida, Tomé, Angelo R, Agostinho, Paula, Cunha, Rodrigo A
Publicado em 2012

Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbens

Por Zappettini, Stefania, Grilli, Massimo, Olivero, Guendalina, Chen, Jiayang, Padolecchia, Cristina, Pittaluga, Anna, Tomé, Angelo R., Cunha, Rodrigo A., Marchi, Mario
Publicado em 2014

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

Por Rial, Daniel, Castro, Adalberto A., Machado, Nuno, Garção, Pedro, Gonçalves, Francisco Q., Silva, Henrique B., Tomé, Ângelo R., Köfalvi, Attila, Corti, Olga, Raisman-Vozari, Rita, Cunha, Rodrigo A., Prediger, Rui D.
Publicado no PLoS One (2014)

Treatment with A(2A) receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage

Por Boia, Raquel, Elvas, Filipe, Madeira, Maria H, Aires, Inês D, Rodrigues-Neves, Ana C, Tralhão, Pedro, Szabó, Eszter C, Baqi, Younis, Müller, Christa E, Tomé, Ângelo R, Cunha, Rodrigo A, Ambrósio, António F, Santiago, Ana R
Publicado no Cell Death Dis (2017)

Caffeine acts through neuronal adenosine A(2A) receptors to prevent mood and memory dysfunction triggered by chronic stress

Por Kaster, Manuella P., Machado, Nuno J., Silva, Henrique B., Nunes, Ana, Ardais, Ana Paula, Santana, Magda, Baqi, Younis, Müller, Christa E., Rodrigues, Ana Lúcia S., Porciúncula, Lisiane O., Chen, Jiang Fan, Tomé, Ângelo R., Agostinho, Paula, Canas, Paula M., Cunha, Rodrigo A.
Publicado no Proc Natl Acad Sci U S A (2015)

Optogenetic activation of intracellular adenosine A(2A) receptor signaling in hippocampus is sufficient to trigger CREB phosphorylation and impair memory

Por Li, Ping, Rial, Daniel, Canas, Paula M., Yoo, Ji-Hoon, Li, Wei, Zhou, Xiangtian, Wang, Yumei, van Westen, Gerard J.P., Payen, Marie-Pierre, Augusto, Elisabete, Gonçalves, Nélio, Tomé, Angelo R., Li, Zhihui, Wu, Zhongnan, Hou, Xianhua, Zhou, Yuanguo, IJzerman, Ad P., Boyden, Edward S., Cunha, Rodrigo A., Qu, Jia, Chen, Jiang-Fan
Publicado no Mol Psychiatry (2015)