The frequency of naïve and early-activated hapten-specific B cell subsets dictates the efficacy of a therapeutic vaccine against prescription opioid abuse

по Laudenbach, Megan, Baruffaldi, Federico, Vervacke, Jeffrey S, Distefano, Mark D, Titcombe, Philip J, Mueller, Daniel L, Tubo, Noah J, Griffith, Thomas S, Pravetoni, Marco
Опубликовано в: J Immunol (2015)

Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells

по Joshua, Vijay, Schobers, Loes, Titcombe, Philip J., Israelsson, Lena, Rönnelid, Johan, Hansson, Monika, Catrina, Anca I., Pruijn, Ger J. M., Malmström, Vivianne
Опубликовано в: Arthritis Res Ther (2016)

Macrophage scavenger receptor 1 (Msr1, SR-A) influences B cell autoimmunity by regulating soluble autoantigen concentration

по Haasken, Stefanie, Auger, Jennifer L., Taylor, Justin J., Hobday, Patricia M., Goudy, Brian D., Titcombe, Philip J., Mueller, Daniel L., Binstadt, Bryce A.
Опубликовано 2013

In Epigenomic Studies, Including Cell-Type Adjustments in Regression Models Can Introduce Multicollinearity, Resulting in Apparent Reversal of Direction of Association

по Barton, Sheila J., Melton, Phillip E., Titcombe, Philip, Murray, Robert, Rauschert, Sebastian, Lillycrop, Karen A., Huang, Rae-Chi, Holbrook, Joanna D., Godfrey, Keith M.
Опубликовано в: Front Genet (2019)

Level and change in bone microarchitectural parameters and their relationship with previous fracture and established bone mineral density loci

по Fuggle, Nicholas R, Westbury, Leo D, Bevilacqua, Gregorio, Titcombe, Philip, Breasail, Mícheál Ó, Harvey, Nicholas C, Dennison, Elaine M, Cooper, Cyrus, Ward, Kate A
Опубликовано в: Bone (2021)

Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen

по Taylor, Justin J., Martinez, Ryan J., Titcombe, Philip J., Barsness, Laura O., Thomas, Stephanie R., Zhang, Na, Katzman, Shoshana D., Jenkins, Marc K., Mueller, Daniel L.
Опубликовано 2012

Immunoglobulin characteristics and RNAseq data of FcRL4+ B cells sorted from synovial fluid and tissue of patients with rheumatoid arthritis

по Amara, Khaled, Clay, Elizabeth, Yeo, Lorraine, Ramsköld, Daniel, Spengler, Julia, Sippl, Natalie, Cameron, James, Israelsson, Lena, Titcombe, Philip J., Grönwall, Caroline, Sahbudin, Ilfita, Filer, Andrew, Raza, Karim, Malmström, Vivianne, Scheel-Toellner, Dagmar
Опубликовано в: Data Brief (2017)

Maternal serum retinol and β-carotene concentrations and neonatal bone mineralization: results from the Southampton Women’s Survey cohort(1)

по Händel, Mina N, Moon, Rebecca J, Titcombe, Philip, Abrahamsen, Bo, Heitmann, Berit L, Calder, Philip C, Dennison, Elaine M, Robinson, Sian M, Godfrey, Keith M, Inskip, Hazel M, Cooper, Cyrus, Harvey, Nicholas C
Опубликовано в: Am J Clin Nutr (2016)

B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis

по Amara, Khaled, Clay, Elizabeth, Yeo, Lorraine, Ramsköld, Daniel, Spengler, Julia, Sippl, Natalie, Cameron, James A., Israelsson, Lena, Titcombe, Philip J., Grönwall, Caroline, Sahbudin, Ilfita, Filer, Andrew, Raza, Karim, Malmström, Vivianne, Scheel-Toellner, Dagmar
Опубликовано в: J Autoimmun (2017)

Perinatal DNA Methylation at CDKN2A Is Associated With Offspring Bone Mass: Findings From the Southampton Women's Survey

по Curtis, Elizabeth M, Murray, Robert, Titcombe, Philip, Cook, Eloïse, Clarke‐Harris, Rebecca, Costello, Paula, Garratt, Emma, Holbrook, Joanna D, Barton, Sheila, Inskip, Hazel, Godfrey, Keith M, Bell, Christopher G, Cooper, Cyrus, Lillycrop, Karen A, Harvey, Nicholas C
Опубликовано в: J Bone Miner Res (2017)

Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA

по Thomas, Stefani N., Altawallbeh, Ghaith, Zaun, Christopher P., Pape, Kathryn A., Peters, Jennifer M., Titcombe, Philip J., Dileepan, Thamotharampillai, Rapp, Michael J., Bold, Tyler D., Schacker, Timothy W., Arbefeville, Sophie, Ferrieri, Patricia, Thyagarajan, Bharat, Jenkins, Marc K., Karger, Amy B.
Опубликовано в: Clin Biochem (2021)

Pathogenic citrulline-multispecific B cell receptor clades in rheumatoid arthritis

по Titcombe, Philip J., Wigerblad, Gustaf, Sippl, Natalie, Zhang, Na, Shmagel, Anna K., Sahlström, Peter, Zhang, Yue, Barsness, Laura O., Ghodke-Puranik, Yogita, Baharpoor, Azar, Hansson, Monika, Israelsson, Lena, Skriner, Karl, Niewold, Timothy B., Klareskog, Lars, Svensson, Camilla I., Amara, Khaled, Malmström, Vivianne, Mueller, Daniel L.
Опубликовано в: Arthritis Rheumatol (2018)

Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial

по Antoun, Elie, Kitaba, Negusse T., Titcombe, Philip, Dalrymple, Kathryn V., Garratt, Emma S., Barton, Sheila J., Murray, Robert, Seed, Paul T., Holbrook, Joanna D., Kobor, Michael S., Lin, David TS, MacIsaac, Julia L., Burdge, Graham C., White, Sara L., Poston, Lucilla, Godfrey, Keith M., Lillycrop, Karen A.
Опубликовано в: PLoS Med (2020)

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis

по Lloyd, Katy A., Wigerblad, Gustaf, Sahlström, Peter, Garimella, Manasa G., Chemin, Karine, Steen, Johanna, Titcombe, Philip J., Marklein, Bianka, Zhou, Diana, Stålesen, Ragnhild, Ossipova, Elena, Lundqvist, Christina, Ekwall, Olov, Rönnelid, Johan, Mueller, Daniel L., Karlsson, Mikael C. I., Kaplan, Mariana J., Skriner, Karl, Klareskog, Lars, Wermeling, Fredrik, Malmström, Vivianne, Grönwall, Caroline
Опубликовано в: Front Immunol (2019)

Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell–Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis...

по Steen, Johanna, Forsström, Björn, Sahlström, Peter, Odowd, Victoria, Israelsson, Lena, Krishnamurthy, Akilan, Badreh, Sara, Mathsson Alm, Linda, Compson, Joanne, Ramsköld, Daniel, Ndlovu, Welcome, Rapecki, Stephen, Hansson, Monika, Titcombe, Philip J., Bang, Holger, Mueller, Daniel L., Catrina, Anca I., Grönwall, Caroline, Skriner, Karl, Nilsson, Peter, Lightwood, Daniel, Klareskog, Lars, Malmström, Vivianne
Опубликовано в: Arthritis Rheumatol (2019)

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis

по Grönwall, Caroline, Liljefors, Lisa, Bang, Holger, Hensvold, Aase H., Hansson, Monika, Mathsson-Alm, Linda, Israelsson, Lena, Joshua, Vijay, Svärd, Anna, Stålesen, Ragnhild, Titcombe, Philip J., Steen, Johanna, Piccoli, Luca, Sherina, Natalia, Clavel, Cyril, Svenungsson, Elisabet, Gunnarsson, Iva, Saevarsdottir, Saedis, Kastbom, Alf, Serre, Guy, Alfredsson, Lars, Malmström, Vivianne, Rönnelid, Johan, Catrina, Anca I., Lundberg, Karin, Klareskog, Lars
Опубликовано в: Front Immunol (2021)

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

по Lillycrop, Karen A., Garratt, Emma S., Titcombe, Philip, Melton, Phillip E., Murray, Robert J. S., Barton, Sheila J., Clarke-Harris, Rebecca, Costello, Paula M., Holbrook, Joanna D., Hopkins, James C., Childs, Caroline E., Paras-Chavez, Carolina, Calder, Philip C., Mori, Trevor A., Beilin, Lawrie, Burdge, Graham C., Gluckman, Peter D., Inskip, Hazel M., Harvey, Nicholas C., Hanson, Mark A., Huang, Rae-Chi, Cooper, Cyrus, Godfrey, Keith M.
Опубликовано в: Int J Obes (Lond) (2019)

Metabolomic Identification of a Novel Pathway of Blood Pressure Regulation Involving Hexadecanedioate

по Menni, Cristina, Graham, Delyth, Kastenmüller, Gabi, Alharbi, Nora H.J., Alsanosi, Safaa Md, McBride, Martin, Mangino, Massimo, Titcombe, Philip, Shin, So-Youn, Psatha, Maria, Geisendorfer, Thomas, Huber, Anja, Peters, Annette, Wang-Sattler, Rui, Xu, Tao, Brosnan, Mary Julia, Trimmer, Jeff, Reichel, Christian, Mohney, Robert P., Soranzo, Nicole, Edwards, Mark H., Cooper, Cyrus, Church, Alistair C., Suhre, Karsten, Gieger, Christian, Dominiczak, Anna F., Spector, Tim D., Padmanabhan, Sandosh, Valdes, Ana M.
Опубликовано в: Hypertension (2015)

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

по Lillycrop, Karen, Murray, Robert, Cheong, Clara, Teh, Ai Ling, Clarke-Harris, Rebecca, Barton, Sheila, Costello, Paula, Garratt, Emma, Cook, Eloise, Titcombe, Philip, Shunmuganathan, Bhuvaneshwari, Liew, Samantha J., Chua, Yong-Cai, Lin, Xinyi, Wu, Yonghui, Burdge, Graham C., Cooper, Cyrus, Inskip, Hazel M., Karnani, Neerja, Hopkins, James C., Childs, Caroline E., Chavez, Carolina Paras, Calder, Philip C., Yap, Fabian, Lee, Yung Seng, Chong, Yap Seng, Melton, Philip E., Beilin, Lawrie, Huang, Rae-Chi, Gluckman, Peter D., Harvey, Nick, Hanson, Mark A., Holbrook, Joanna D., Godfrey, Keith M.
Опубликовано в: EBioMedicine (2017)

Mitochondrial oxidative capacity and NAD(+) biosynthesis are reduced in human sarcopenia across ethnicities

по Migliavacca, Eugenia, Tay, Stacey K. H., Patel, Harnish P., Sonntag, Tanja, Civiletto, Gabriele, McFarlane, Craig, Forrester, Terence, Barton, Sheila J., Leow, Melvin K., Antoun, Elie, Charpagne, Aline, Seng Chong, Yap, Descombes, Patrick, Feng, Lei, Francis-Emmanuel, Patrice, Garratt, Emma S., Giner, Maria Pilar, Green, Curtis O., Karaz, Sonia, Kothandaraman, Narasimhan, Marquis, Julien, Metairon, Sylviane, Moco, Sofia, Nelson, Gail, Ngo, Sherry, Pleasants, Tony, Raymond, Frederic, Sayer, Avan A., Ming Sim, Chu, Slater-Jefferies, Jo, Syddall, Holly E., Fang Tan, Pei, Titcombe, Philip, Vaz, Candida, Westbury, Leo D., Wong, Gerard, Yonghui, Wu, Cooper, Cyrus, Sheppard, Allan, Godfrey, Keith M., Lillycrop, Karen A., Karnani, Neerja, Feige, Jerome N.
Опубликовано в: Nat Commun (2019)