Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells

BACKGROUND: Antibodies against citrullinated proteins (ACPA) are common in patients with rheumatoid arthritis (RA). ACPA can appear before disease onset and target many self-antigens. Citrullinated fibrin/fibrinogen represents a classical ACPA target antigen, and mass spectrometry of RA synovial flu...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Joshua, Vijay, Schobers, Loes, Titcombe, Philip J., Israelsson, Lena, Rönnelid, Johan, Hansson, Monika, Catrina, Anca I., Pruijn, Ger J. M., Malmström, Vivianne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133744/
https://ncbi.nlm.nih.gov/pubmed/27906052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1181-0
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