News from the dark side!

Por Thwaites, David T
Publicado em 2012

Fishing with flies, worms and bacteria: emerging models for mammalian membrane transport and trafficking

Por Thwaites, David T
Publicado em 2014

The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport

Por Thwaites, David T, Anderson, Catriona MH
Publicado em 2011

Regulation of intestinal hPepT1 (SLC15A1) activity by phosphodiesterase inhibitors is via inhibition of NHE3 (SLC9A3)

Por Anderson, Catriona M.H., Thwaites, David T.
Publicado em 2007

H(+)-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine

Por Thwaites, David T., Anderson, Catriona M.H.
Publicado em 2007

Human solute carrier SLC6A14 is the β-alanine carrier

Por Anderson, Catriona M H, Ganapathy, Vadivel, Thwaites, David T
Publicado em 2008

H(+)/solute-induced intracellular acidification leads to selective activation of apical Na(+)/H(+) exchange in human intestinal epithelial cells

Por Thwaites, David T., Ford, Dianne, Glanville, Michael, Simmons, Nicholas L.
Publicado em 1999

Substrate specificity and functional characterisation of the H(+)/amino acid transporter rat PAT2 (Slc36a2)

Por Kennedy, David J, Gatfield, Kelly M, Winpenny, John P, Ganapathy, Vadivel, Thwaites, David T
Publicado em 2004

Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H(+)-coupled amino-acid transporter hPAT1

Por Abbot, Emily L, Grenade, Danielle S, Kennedy, David J, Gatfield, Kelly M, Thwaites, David T
Publicado em 2005

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

Por Walker, Dianne, Thwaites, David T, Simmons, Nicholas L, Gilbert, Harry J, Hirst, Barry H
Publicado em 1998

Inhibition of intestinal dipeptide transport by the neuropeptide VIP is an anti-absorptive effect via the VPAC(1) receptor in a human enterocyte-like cell line (Caco-2)

Por Anderson, Catriona M H, Mendoza, Maria E, Kennedy, David J, Raldua, Demetrio, Thwaites, David T
Publicado em 2003

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H(+)-coupled PAT1 (SLC36A1) and Na(+)- and Cl(−)-dependent TauT (SLC6A6)

Por Anderson, Catriona M H, Howard, Alison, Walters, Julian R F, Ganapathy, Vadivel, Thwaites, David T
Publicado em 2009

Gamma-aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers

Por Thwaites, David T, Basterfield, Laura, McCleave, Peter M J, Carter, Simon M, Simmons, Nicholas L
Publicado em 2000

Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2)

Por Edwards, Noel, Anderson, Catriona M.H., Gatfield, Kelly M., Jevons, Mark P., Ganapathy, Vadivel, Thwaites, David T.
Publicado em 2011

Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H(+)-Coupled Nutrient Carriers Coexpressed in the Small Intestine

Por Anderson, Catriona M. H., Jevons, Mark, Thangaraju, Muthusamy, Edwards, Noel, Conlon, Nichola J., Woods, Steven, Ganapathy, Vadivel, Thwaites, David T.
Publicado em 2010

Rapid learning in practice: A lung cancer survival decision support system in routine patient care data

Por Dekker, Andre, Vinod, Shalini, Holloway, Lois, Oberije, Cary, George, Armia, Goozee, Gary, Delaney, Geoff P., Lambin, Philippe, Thwaites, David
Publicado no Radiother Oncol (2014)

Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2

Por Chen, Zhong, Fei, You-Jun, Anderson, Catriona M H, Wake, Katherine A, Miyauchi, Seiji, Huang, Wei, Thwaites, David T, Ganapathy, Vadivel
Publicado em 2003

Implementation of a rapid learning platform: Predicting 2-year survival in laryngeal carcinoma patients in a clinical setting

Por Lustberg, Tim, Bailey, Michael, Thwaites, David I., Miller, Alexis, Carolan, Martin, Holloway, Lois, Velazquez, Emmanuel Rios, Hoebers, Frank, Dekker, Andre
Publicado no Oncotarget (2016)

Prostate motion during radiotherapy of prostate cancer patients with and without application of a hydrogel spacer: a comparative study

Por Juneja, Prabhjot, Kneebone, Andrew, Booth, Jeremy T., Thwaites, David I., Kaur, Ramandeep, Colvill, Emma, Ng, Jin A., Keall, Paul J., Eade, Thomas
Publicado no Radiat Oncol (2015)

Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials

Por Clark, Catharine H, Aird, Edwin GA, Bolton, Steve, Miles, Elizabeth A, Nisbet, Andrew, Snaith, Julia AD, Thomas, Russell AS, Venables, Karen, Thwaites, David I
Publicado no Br J Radiol (2015)