New therapeutic targets in rheumatoid arthritis

Por Tak, Paul-Peter
Publicado em 2009

Anti-interleukin 6 receptor therapy for hyper-IgD syndrome

Por Musters, Anne, Tak, Paul Peter, Baeten, Dominique L P, Tas, Sander W
Publicado no BMJ Case Rep (2015)

IL-17 producing mast cells contribute to synovial inflammation in non-psoriatic and psoriatic spondyloarthritis

Por Noordenbos, Troy, Yeremenko, Nataliya, Gofita, Ioana, Tak, Paul Peter, Cañete, Juan, Baeten, Dominique
Publicado em 2011

Flt3 inhibition leads to decreased production of IL-6 by synovial biopsies and fibroblast-like synoviocytes by reducing NFKb activity

Por Ramos, M Inês, Korchynskyi, Olexandr, Aarrass, Saida, Tak, Paul Peter, Lebre, M Cristina
Publicado em 2011

Non-canonical NF-κB signaling in endothelial cells may enhance synovial inflammation by stimulating angiogenesis

Por Noort, Ae-Ri, van Zoest, Katinka PM, Tak, Paul Peter, Tas, Sander W
Publicado em 2011

Identification of robust and disease-specific stromal alterations in spondyloarthritis synovitis

Por Yeremenko, Nataliya, Noordenbos, Troy, Rigter, Gemma, Cañete, Juan, Tak, Paul-Peter, Baeten, Dominique
Publicado em 2011

Triggering of viral RNA sensors induces CD55 expression on synovial fibroblasts

Por Karpus, Olga N, Heutinck, Kirstin M, Wijnker, Paul JM, Tak, Paul Peter, Hamann, Jorg
Publicado em 2011

Immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10

Por Ambarus, Carmen, Geurts-van Bon, Lenny, Wenink, Mark, Tak, Paul Peter, Radstake, Timothy, Baeten, Dominique
Publicado em 2011

NF-kappaB inducing kinase (NIK) is a key regulator of inflammation-induced angiogenesis

Por Noort, Ae-Ri, van Zoest, Katinka PM, Koolwijk, Pieter, Tak, Paul-Peter, Tas, Sander W
Publicado em 2012

Serum biomarkers to predict clinical response in proof-of-concept trials in spondyloarthritis

Por Turina, Maureen, Yeremenko, Nataliya, Paramarta, Jacqueline, Vandooren, Bernard, Tak, Paul Peter, De Rycke, Leen, Baeten, Dominique
Publicado em 2011

Extrathymic Autoimmune Regulator (AIRE) expression in rheumatoid arthritis

Por Noort, Ae-Ri, van Zoest, Katinka PM, Lebre, M Christina, Tak, Paul-Peter, Tas, Sander W
Publicado em 2012

DNA Methylome Signature in Early Rheumatoid Arthritis Synoviocytes Compared with Longstanding Rheumatoid Arthritis Synoviocytes

Por Ai, Rizi, Whitaker, John W., Boyle, David L., Tak, Paul Peter, Gerlag, Danielle M., Wang, Wei, Firestein, Gary S.
Publicado no Arthritis Rheumatol (2015)

Neo-Epitopes—Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis

Por Maijer, Karen I., Gudmann, Natasja Stæhr, Karsdal, Morten Asser, Gerlag, Daniëlle M., Tak, Paul Peter, Bay-Jensen, Anne Christine
Publicado no PLoS One (2016)

Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis

Por Barthel, Christian, Yeremenko, Nataliya, Jacobs, Roland, Schmidt, Reinhold E, Bernateck, Michael, Zeidler, Henning, Tak, Paul-Peter, Baeten, Dominique, Rihl, Markus
Publicado em 2009

Neurostimulation of the Cholinergic Anti-Inflammatory Pathway Ameliorates Disease in Rat Collagen-Induced Arthritis

Por Levine, Yaakov A., Koopman, Frieda A., Faltys, Michael, Caravaca, April, Bendele, Alison, Zitnik, Ralph, Vervoordeldonk, Margriet J., Tak, Paul Peter
Publicado em 2014

Hormone, metabolic peptide, and nutrient levels in the earliest phases of rheumatoid arthritis—contribution of free fatty acids to an increased cardiovascular risk during very earl...

Por Tang, Man Wai, Koopman, Frieda A., Visscher, Jan P.M., de Hair, Maria J., Gerlag, Danielle M., Tak, Paul Peter
Publicado no Clin Rheumatol (2016)

Continued inhibition of structural damage over 2 years in patients with rheumatoid arthritis treated with rituximab in combination with methotrexate

Por Cohen, Stanley B, Keystone, Edward, Genovese, Mark C, Emery, Paul, Peterfy, Charles, Tak, Paul Peter, Cravets, Matt, Shaw, Tim, Hagerty, David
Publicado em 2010

The role of Bob1 in rheumatoid arthritis: potential implications for autoimmunity

Por Yeremenko, Nataliya, Cantaert, Tineke, van Tok, Melissa N, Gofita, Ioana, Canete, Juan D, Tak, Paul-Peter, Spits, Hergen, Baeten, Dominique L
Publicado em 2012

Relative overexpression of membrane-bound versus soluble TNF in spondyloarthritis

Por Ambarus Carmen A, van Duivenvoorde Leonie M, Masdar Huriatul, van Tok Melissa N, Tak Paul-Peter, Yeremenko Nataliya G, Baeten Dominique L
Publicado em 2012-11-01

Relative overexpression of membrane-bound versus soluble TNF in spondyloarthritis

Por Ambarus, Carmen A, van Duivenvoorde, Leonie M, Masdar, Huriatul, van Tok, Melissa N, Tak, Paul-Peter, Yeremenko, Nataliya G, Baeten, Dominique L
Publicado em 2012