Neo-Epitopes—Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis

OBJECTIVE: Tissue destruction in rheumatoid arthritis (RA) is predominantly mediated by matrix metalloproteinases (MMPs), thereby generating protein fragments. Previous studies have revealed that these fragments include MMP-mediated collagen type I, II, and III degradation, citrullinated and MMP-deg...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Maijer, Karen I., Gudmann, Natasja Stæhr, Karsdal, Morten Asser, Gerlag, Daniëlle M., Tak, Paul Peter, Bay-Jensen, Anne Christine
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809616/
https://ncbi.nlm.nih.gov/pubmed/27019199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149329
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items