From remote enhancers to gene regulation: charting the genome's regulatory landscapes

by Symmons, Orsolya, Spitz, François
Published 2013

Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences

by Ettwiller, Laurence, Budd, Aidan, Spitz, François, Wittbrodt, Joachim
Published 2008

Uncoupling Time and Space in the Collinear Regulation of Hox Genes

by Tschopp, Patrick, Tarchini, Basile, Spitz, François, Zakany, Jozsef, Duboule, Denis
Published 2009

Charting the regulatory landscape of the mouse genome in vivo

by Symmons, Orsolva, Ettwiller, Laurence, Ruf, Sandra, Uslu, Veli, Spitz, Francois
Published 2013

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

by Spitz, François, Gonzalez, Federico, Peichel, Catherine, Vogt, Thomas F., Duboule, Denis, Zákány, József
Published 2001

Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase

by Kirchmaier, Stephan, Höckendorf, Burkhard, Möller, Eva Katharina, Bornhorst, Dorothee, Spitz, Francois, Wittbrodt, Joachim
Published 2013

A Discrete Transition Zone Organizes the Topological and Regulatory Autonomy of the Adjacent Tfap2c and Bmp7 Genes

by Tsujimura, Taro, Klein, Felix A., Langenfeld, Katja, Glaser, Juliane, Huber, Wolfgang, Spitz, François
Published in PLoS Genet (2015)

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances

by Symmons, Orsolya, Pan, Leslie, Remeseiro, Silvia, Aktas, Tugce, Klein, Felix, Huber, Wolfgang, Spitz, François
Published in Dev Cell (2016)

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

by Spitz, François, Demignon, Josiane, Porteu, Arlette, Kahn, Axel, Concordet, Jean-Paul, Daegelen, Dominique, Maire, Pascal
Published 1998

TRACER: a resource to study the regulatory architecture of the mouse genome

by Chen, Chao-Kung, Symmons, Orsolya, Uslu, Veli Vural, Tsujimura, Taro, Ruf, Sandra, Smedley, Damian, Spitz, François
Published 2013

Functional and topological characteristics of mammalian regulatory domains

by Symmons, Orsolya, Uslu, Veli Vural, Tsujimura, Taro, Ruf, Sandra, Nassari, Sonya, Schwarzer, Wibke, Ettwiller, Laurence, Spitz, François
Published 2014

Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State

by Amin, Shilu, Donaldson, Ian J., Zannino, Denise A., Hensman, James, Rattray, Magnus, Losa, Marta, Spitz, François, Ladam, Franck, Sagerström, Charles, Bobola, Nicoletta
Published in Dev Cell (2015)

Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome

by Liu, Xiaoxi, Tamada, Kota, Kishimoto, Rui, Okubo, Hiroko, Ise, Satoko, Ohta, Hisashi, Ruf, Sandra, Nakatani, Jin, Kohno, Nobuoki, Spitz, François, Takumi, Toru
Published in Genom Data (2015)

Genetic dissection identifies Necdin as a driver gene in a mouse model of paternal 15q duplications

by Tamada, Kota, Fukumoto, Keita, Toya, Tsuyoshi, Nakai, Nobuhiro, Awasthi, Janak R., Tanaka, Shinji, Okabe, Shigeo, Spitz, François, Saitow, Fumihito, Suzuki, Hidenori, Takumi, Toru
Published in Nat Commun (2021)

Genotypic Features of Lentivirus Transgenic Mice

by Sauvain, Marc-Olivier, Dorr, Alexander P., Stevenson, Brian, Quazzola, Alexandra, Naef, Félix, Wiznerowicz, Maciej, Schütz, Frédéric, Jongeneel, Victor, Duboule, Denis, Spitz, François, Trono, Didier
Published 2008

Two independent modes of chromatin organization revealed by cohesin removal

by Schwarzer, Wibke, Abdennur, Nezar, Goloborodko, Anton, Pekowska, Aleksandra, Fudenberg, Geoffrey, Loe-Mie, Yann, Fonseca, Nuno A, Huber, Wolfgang, Haering, Christian, Mirny, Leonid, Spitz, Francois
Published in Nature (2017)

Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression

by Zuniga, Aimée, Michos, Odyssé, Spitz, François, Haramis, Anna-Pavlina G., Panman, Lia, Galli, Antonella, Vintersten, Kristina, Klasen, Christian, Mansfield, William, Kuc, Sylwia, Duboule, Denis, Dono, Rosanna, Zeller, Rolf
Published 2004

A Systematic Enhancer Screen Using Lentivector Transgenesis Identifies Conserved and Non-Conserved Functional Elements at the Olig1 and Olig2 Locus

by Friedli, Marc, Barde, Isabelle, Arcangeli, Mélanie, Verp, Sonia, Quazzola, Alexandra, Zakany, Jozsef, Lin-Marq, Nathalie, Robyr, Daniel, Attanasio, Catia, Spitz, François, Duboule, Denis, Trono, Didier, Antonarakis, Stylianos E.
Published 2010

Six1 and Eya1 Expression Can Reprogram Adult Muscle from the Slow-Twitch Phenotype into the Fast-Twitch Phenotype

by Grifone, Raphaelle, Laclef, Christine, Spitz, François, Lopez, Soledad, Demignon, Josiane, Guidotti, Jacques-Emmanuel, Kawakami, Kiyoshi, Xu, Pin-Xian, Kelly, Robert, Petrof, Basil J., Daegelen, Dominique, Concordet, Jean-Paul, Maire, Pascal
Published 2004

Cis-regulatory architecture of a brain-signaling center predates the origin of chordates

by Yao, Yao, Minor, Paul J., Zhao, Ying-Tao, Jeong, Yongsu, Pani, Ariel M., King, Anna N., Symmons, Orsolya, Gan, Lin, Cardoso, Wellington V., Spitz, François, Lowe, Christopher J., Epstein, Douglas J.
Published in Nat Genet (2016)