Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

The ancestral role of the Hox gene family is specifying morphogenetic differences along the main body axis. In vertebrates, HoxD genes were also co-opted along with the emergence of novel structures such as limbs and genitalia. We propose that these functional recruitments relied on the appearance,...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Spitz, François, Gonzalez, Federico, Peichel, Catherine, Vogt, Thomas F., Duboule, Denis, Zákány, József
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2001
Assuntos:	Research Communication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.205701
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!