Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

The ancestral role of the Hox gene family is specifying morphogenetic differences along the main body axis. In vertebrates, HoxD genes were also co-opted along with the emergence of novel structures such as limbs and genitalia. We propose that these functional recruitments relied on the appearance,...

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Podrobná bibliografie

Vydáno v:	Genes Dev
Hlavní autoři:	Spitz, François, Gonzalez, Federico, Peichel, Catherine, Vogt, Thomas F., Duboule, Denis, Zákány, József
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cold Spring Harbor Laboratory Press 2001
Témata:	Research Communication
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.205701
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