Malaria vaccines: identifying Plasmodium falciparum liver-stage targets

Por Longley, Rhea J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no Front Microbiol (2015)

Solar inactivated Salmonella Typhimurium induces an immune response in BALB/c mice

Por Ssemakalu, Cornelius C., Ulaszewska, Marta, Elias, Sean, Spencer, Alexandra J.
Publicado no Heliyon (2021)

Simian adenoviruses as vaccine vectors

Por Morris, Susan J, Sebastian, Sarah, Spencer, Alexandra J, Gilbert, Sarah C
Publicado no Future Virol (2016)

Deletion of Fifteen Open Reading Frames from Modified Vaccinia Virus Ankara Fails to Improve Immunogenicity

Por Alharbi, Naif Khalaf, Spencer, Alexandra J., Hill, Adrian V. S., Gilbert, Sarah C.
Publicado no PLoS One (2015)

Development of an In Vitro Assay and Demonstration of Plasmodium berghei Liver-Stage Inhibition by TRAP-Specific CD8(+) T Cells

Por Longley, Rhea J., Bauza, Karolis, Ewer, Katie J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no PLoS One (2015)

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens

Por Ewer, Katie, Sebastian, Sarah, Spencer, Alexandra J., Gilbert, Sarah, Hill, Adrian V. S., Lambe, Teresa
Publicado no Hum Vaccin Immunother (2017)

Identification of Immunodominant Responses to the Plasmodium falciparum Antigens PfUIS3, PfLSA1 and PfLSAP2 in Multiple Strains of Mice

Por Longley, Rhea J., Halbroth, Benedict R., Ewer, Katie J., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no PLoS One (2015)

The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8(+) T Cells Present in the Liver

Por Spencer, Alexandra J., Longley, Rhea J., Gola, Anita, Ulaszewska, Marta, Lambe, Teresa, Hill, Adrian V. S.
Publicado no J Immunol (2017)

Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

Por Cottingham, Matthew G., Andersen, Rikke F., Spencer, Alexandra J., Saurya, Saroj, Furze, Julie, Hill, Adrian V. S., Gilbert, Sarah C.
Publicado em 2008

Correction: Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

Por Cottingham, Matthew G., Andersen, Rikke F., Spencer, Alexandra J., Saurya, Saroj, Furze, Julie, Hill, Adrian V. S., Gilbert, Sarah C.
Publicado em 2011

Development of a Molecular Adjuvant to Enhance Antigen-Specific CD8(+) T Cell Responses

Por Halbroth, Benedict R., Sebastian, Sarah, Poyntz, Hazel C., Bregu, Migena, Cottingham, Matthew G., Hill, Adrian V. S., Spencer, Alexandra J.
Publicado no Sci Rep (2018)

Recombinant Viral Vectored Vaccines Expressing Plasmodium chabaudi AS Apical Membrane Antigen 1: Mechanisms of Vaccine-Induced Blood-Stage Protection

Por Biswas, Sumi, Spencer, Alexandra J., Forbes, Emily K., Gilbert, Sarah C., Holder, Anthony A., Hill, Adrian V. S., Draper, Simon J.
Publicado em 2012

The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species

Por Dicks, Matthew D.J., Guzman, Efrain, Spencer, Alexandra J., Gilbert, Sarah C., Charleston, Bryan, Hill, Adrian V.S., Cottingham, Matthew G.
Publicado no Vaccine (2015)

Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice

Por Dicks, Matthew D. J., Spencer, Alexandra J., Coughlan, Lynda, Bauza, Karolis, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Publicado no Sci Rep (2015)

Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice

Por Brod, Florian, Miura, Kazutoyo, Taylor, Iona, Li, Yuanyuan, Marini, Arianna, Salman, Ahmed M., Spencer, Alexandra J., Long, Carole A., Biswas, Sumi
Publicado no Front Immunol (2018)

Modification of Adenovirus vaccine vector-induced immune responses by expression of a signalling molecule

Por Rollier, Christine S., Spencer, Alexandra J., Sogaard, Karen Colbjorn, Honeycutt, Jared, Furze, Julie, Bregu, Migena, Gilbert, Sarah C., Wyllie, David, Hill, Adrian V. S.
Publicado no Sci Rep (2020)

A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

Por Dicks, Matthew D. J., Spencer, Alexandra J., Edwards, Nick J., Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Publicado em 2012

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

Por Longley, Rhea J., Salman, Ahmed M., Cottingham, Matthew G., Ewer, Katie, Janse, Chris J., Khan, Shahid M., Spencer, Alexandra J., Hill, Adrian V. S.
Publicado no Sci Rep (2015)

Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1

Por Lambe, Teresa, Carey, John B., Li, Yuanyuan, Spencer, Alexandra J., van Laarhoven, Arjan, Mullarkey, Caitlin E., Vrdoljak, Anto, Moore, Anne C., Gilbert, Sarah C.
Publicado em 2013

A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector

Por Sebastian, Sarah, Flaxman, Amy, Cha, Kuan M., Ulaszewska, Marta, Gilbride, Ciaran, Sharpe, Hannah, Wright, Edward, Spencer, Alexandra J., Dowall, Stuart, Hewson, Roger, Gilbert, Sarah, Lambe, Teresa
Publicado no Vaccines (Basel) (2020)