Significance of antibodies to cytoplasmic components of neutrophils.

Por Specks, U, DeRemee, R A
Publicado em 1989

Human mast cells expressing recombinant proteinase 3 (PR3) as substrate for clinical testing for anti-neutrophil cytoplasmic antibodies (ANCA)

Por SPECKS, U, WIEGERT, E M, HOMBURGER, H A
Publicado em 1997

Structure of recombinant N-terminal globule of type VI collagen alpha 3 chain and its binding to heparin and hyaluronan.

Por Specks, U, Mayer, U, Nischt, R, Spissinger, T, Mann, K, Timpl, R, Engel, J, Chu, M L
Publicado em 1992

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide

Por Sun, J, Fass, D N, Viss, M A, Hummel, A M, Tang, H, Homburger, H A, Specks, U
Publicado em 1998

Agreement of anti-neutrophil cytoplasmic antibody measurements obtained from serum and plasma

Por Lee, A S, Finkielman, J D, Peikert, T, Hummel, A M, Viss, M A, Jacob, G L, Homburger, H A, Specks, U
Publicado em 2006

Comparison of disease activity measures for anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis

Por Merkel, PA, Cuthbertson, DD, Hellmich, B, Hoffman, GS, Jayne, DRW, Kallenberg, CGM, Krischer, JP, Luqmani, R, Mahr, AD, Matteson, EL, Specks, U, Stone, JH
Publicado em 2008

Glycosylation of proteinase 3 (PR3) is not required for its reactivity with antineutrophil cytoplasmic antibodies (ANCA) in Wegener’s granulomatosis

Por Finkielman, J.D., Merkel, P.A., Schroeder, D., Hoffman, G.S., Spiera, R., St. Clair, E.W., Davis, J.C., McCune, W.J., Lears, A., Ytterberg, S.R., Hummel, A.M., Viss, M.A., Peikert, T., Stone, J.H., Specks, U.
Publicado em 2009

Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis

Por Wechsler, M.E., Akuthota, P., Jayne, D., Khoury, P., Klion, A., Langford, C.A., Merkel, P.A., Moosig, F., Specks, U., Cid, M.C., Luqmani, R., Brown, J., Mallett, S., Philipson, R., Yancey, S.W., Steinfeld, J., Weller, P.F., Gleich, G.J.
Publicado no N Engl J Med (2017)

Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis

Por Clain, J. M., Hummel, A. M., Stone, J. H., Fervenza, F. C., Hoffman, G. S., Kallenberg, C. G. M., Langford, C. A., McCune, W. J., Merkel, P. A., Monach, P. A., Seo, P., Spiera, R. F., St Clair, E. W., Ytterberg, S. R., Specks, U.
Publicado no Clin Exp Immunol (2017)

Rituximab for the Treatment of Relapses in ANCA-associated Vasculitis

Por Miloslavsky, EM, Specks, U, Merkel, PA, Seo, P, Spiera, R, Langford, CA, Hoffman, GS, Kallenberg, CGM, St. Clair, EW, Tchao, NK, Viviano, L, Ding, L, Ikle, D, Villarreal, M, Jepson, B, Brunetta, P, Allen, NB, Fervenza, FC, Geetha, D, Keogh, K, Kissin, EY, Monach, PA, Peikert, T, Stegeman, C, Ytterberg, SR, Stone, JH
Publicado no Arthritis Rheumatol (2014)

Clinical Outcomes of Remission Induction Therapy for Severe Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Por Miloslavsky, E. M., Specks, U., Merkel, P. A., Seo, P., Spiera, R., Langford, C. A., Hoffman, G. S., Kallenberg, C. G. M., St.Clair, E. W., Tchao, N. K., Viviano, L., Ding, L., Sejismundo, L. P., Mieras, K., Iklé, D., Jepson, B., Mueller, M., Brunetta, P., Allen, N. B., Fervenza, F. C., Geetha, D., Keogh, K., Kissin, E. Y., Monach, P. A., Peikert, T., Stegeman, C., Ytterberg, S. R., Stone, J. H.
Publicado no Arthritis Rheum (2013)