ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK

由 Filippov, Sergey, Pinkosky, Stephen L., Lister, Richard J., Pawloski, Catherine, Hanselman, Jeffrey C., Cramer, Clay T., Srivastava, Rai Ajit K., Hurley, Timothy R., Bradshaw, Cheryl D., Spahr, Mark A., Newton, Roger S.
出版 2013

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism

由 Pinkosky, Stephen L., Filippov, Sergey, Srivastava, Rai Ajit K., Hanselman, Jeffrey C., Bradshaw, Cheryl D., Hurley, Timothy R., Cramer, Clay T., Spahr, Mark A., Brant, Ashley F., Houghton, Jacob L., Baker, Chris, Naples, Mark, Adeli, Khosrow, Newton, Roger S.
出版 2013

Inhibiting Oxidative Phosphorylation in Vivo Restrains T(H)17 Effector Responses and Ameliorates Murine Colitis()

由 Franchi, Luigi, Monteleone, Ivan, Hao, Ling-Yang, Spahr, Mark, Zhao, Wenpu, Liu, Xikui, Demock, Kellie, Kulkarni, Aditi, Lesch, Chuck A., Sanchez, Brian, Carter, Laura, Marafini, Irene, Hu, Xiao, Mashadova, Oksana, Yuan, Min, Asara, John M., Singh, Harinder, Lyssiotis, Costas A., Monteleone, Giovanni, Opipari, Anthony W., Glick, Gary D.
發表在 J Immunol (2017)