Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involvin...

Por Soos, M A, Siddle, K
Publicado em 1989

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity.

Por Soos, M A, Field, C E, Siddle, K
Publicado em 1993

Monoclonal antibodies to the insulin receptor stimulate the intrinsic tyrosine kinase activity by cross-linking receptor molecules.

Por O'Brien, R M, Soos, M A, Siddle, K
Publicado em 1987

Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells.

Por Soos, M A, Whittaker, J, Lammers, R, Ullrich, A, Siddle, K
Publicado em 1990

Complement-induced Ca2+ influx in cultured fibroblasts is decreased by the calcium-channel antagonist nifedipine or by some bivalent inorganic cations.

Por Newsholme, P, Adogu, A A, Soos, M A, Hales, C N
Publicado em 1993

Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.

Por Taylor, R, Soos, M A, Wells, A, Argyraki, M, Siddle, K
Publicado em 1987

Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat...

Por Whitehead, J P, Soos, M A, Aslesen, R, O'rahilly, S, Jensen, J
Publicado em 2000

Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotti...

Por Bailyes, E M, Navé, B T, Soos, M A, Orr, S R, Hayward, A C, Siddle, K
Publicado em 1997

A monoclonal anti-peptide antibody reacting with the insulin receptor beta-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intac...

Por Ganderton, R H, Stanley, K K, Field, C E, Coghlan, M P, Soos, M A, Siddle, K
Publicado em 1992

Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective...

Por Dib, K, Whitehead, J P, Humphreys, P J, Soos, M A, Baynes, K C, Kumar, S, Harvey, T, O'Rahilly, S
Publicado em 1998

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.

Por Soos, M A, Siddle, K, Baron, M D, Heward, J M, Luzio, J P, Bellatin, J, Lennox, E S
Publicado em 1986

Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts.

Por Soos, M A, O'Brien, R M, Brindle, N P, Stigter, J M, Okamoto, A K, Whittaker, J, Siddle, K
Publicado em 1989

Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors.

Por Treadway, J L, Morrison, B D, Soos, M A, Siddle, K, Olefsky, J, Ullrich, A, McClain, D A, Pessin, J E
Publicado em 1991

Treatment of Type B Insulin Resistance: A Novel Approach to Reduce Insulin Receptor Autoantibodies

Por Malek, R., Chong, A. Y., Lupsa, B. C., Lungu, A. O., Cochran, E. K., Soos, M. A., Semple, R. K., Balow, J. E., Gorden, P.
Publicado em 2010

IRS2 variants and syndromes of severe insulin resistance

Por Bottomley, W. E., Soos, M. A., Adams, C., Guran, T., Howlett, T. A., Mackie, A., Miell, J., Monson, J. P., Temple, R., Tenenbaum-Rakover, Y., Tymms, J., Savage, D. B., Semple, R.K., O'Rahilly, S., Barroso, I.
Publicado em 2009

Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recycling

Por Raffan, E., Soos, M. A., Rocha, N., Tuthill, A., Thomsen, A. R., Hyden, C. S., Gregory, J. W., Hindmarsh, P., Dattani, M., Cochran, E., Al Kaabi, J., Gorden, P., Barroso, I., Morling, N., O’Rahilly, S., Semple, R. K.
Publicado em 2011