EXPERIMENTALLY INCREASING TITIN’S COMPLIANCE THROUGH RBM20 INHIBITION IMPROVES DIASTOLIC FUNCTION IN A MOUSE MODEL OF HFpEF

von Methawasin, Mei, Strom, Joshua G, Slater, Rebecca E, Fernandez, Vanessa, Saripalli, Chandra, Granzier, Henk
Veröffentlicht in Circulation (2016)

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance

von Slater, Rebecca E., Strom, Joshua G., Methawasin, Mei, Liss, Martin, Gotthardt, Michael, Sweitzer, Nancy, Granzier, Henk L.
Veröffentlicht in J Gen Physiol (2019)

Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function

von Granzier, Henk L., Hutchinson, Kirk R., Tonino, Paola, Methawasin, Mei, Li, Frank W., Slater, Rebecca E., Bull, Mathew M., Saripalli, Chandra, Pappas, Christopher T., Gregorio, Carol C., Smith, John E.
Veröffentlicht 2014