EXPERIMENTALLY INCREASING TITIN’S COMPLIANCE THROUGH RBM20 INHIBITION IMPROVES DIASTOLIC FUNCTION IN A MOUSE MODEL OF HFpEF

Por Methawasin, Mei, Strom, Joshua G, Slater, Rebecca E, Fernandez, Vanessa, Saripalli, Chandra, Granzier, Henk
Publicado no Circulation (2016)

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance

Por Slater, Rebecca E., Strom, Joshua G., Methawasin, Mei, Liss, Martin, Gotthardt, Michael, Sweitzer, Nancy, Granzier, Henk L.
Publicado no J Gen Physiol (2019)

Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function

Por Granzier, Henk L., Hutchinson, Kirk R., Tonino, Paola, Methawasin, Mei, Li, Frank W., Slater, Rebecca E., Bull, Mathew M., Saripalli, Chandra, Pappas, Christopher T., Gregorio, Carol C., Smith, John E.
Publicado em 2014