Sm-p80-based schistosomiasis vaccine: Preparation for human clinical trials

Por Siddiqui, Afzal A., Siddiqui, Sabrina Z.
Publicado no Trends Parasitol (2016)

Sm-p80-based DNA vaccine made in a human use approved vector VR1020 protects against challenge infection with Schistosoma mansoni in mouse

Por Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Siddiqui, Afzal A.
Publicado em 2009

Role of antibodies in Sm-p80-mediated protection against Schistosoma mansoni challenge infection in murine and nonhuman primate models

Por Torben, Workineh, Ahmad, Gul, Zhang, Weidong, Siddiqui, Afzal A.
Publicado em 2011

Schistosoma mansoni antigen Sm-p80: Prophylactic efficacy of a vaccine formulated in human approved plasmid vector and adjuvant (VR 1020 and alum)

Por Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Siddiqui, Afzal A.
Publicado em 2011

Schistosomiasis vaccines

Por Siddiqui, Afzal A., Siddiqui, Bilal A., Ganley-Leal, Lisa
Publicado em 2011

Hepatitis B Vaccines and HPV Vaccines Have Been Hailed as Major Public Health Achievements in Preventing Cancer—Could a Schistosomiasis Vaccine be the Third?

Por Hsieh, Michael H., Brotherton, Julia M. L., Siddiqui, Afzal A.
Publicado no PLoS Negl Trop Dis (2015)

Protective effects of Sm-p80 in the presence of resiquimod as an adjuvant against challenge infection with Schistosoma mansoni in mice

Por Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Noor, Zahid, Siddiqui, Afzal A.
Publicado em 2010

Role of antibody dependent cell mediated cytotoxicity (ADCC) in Sm-p80-mediated protection against Schistosoma mansoni

Por Torben, Workineh, Ahmad, Gul, Zhang, Weidong, Nash, Stewart, Le, Loc, Karmakar, Souvik, Siddiqui, Afzal A.
Publicado em 2012

Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by th...

Por Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Haskins, Chad, Diggs, Sue, Noor, Zahid, Le, Loc, Siddiqui, Afzal A.
Publicado em 2009

Development of a Schistosomiasis Vaccine

Por Molehin, Adebayo J., Rojo, Juan U., Siddiqui, Sabrina Z., Gray, Sean A., Carter, Darrick, Siddiqui, Afzal A.
Publicado no Expert Rev Vaccines (2016)

Priming of a β-Galactosidase (β-GAL)-Specific Type 1 Response in BALB/c Mice Infected with β-GAL-Transfected Leishmania major

Por Chakkalath, Hrishekesh R., Siddiqui, Afzal A., Shankar, Anuraj H., Dobson, Deborah E., Beverley, Stephen M., Titus, Richard G.
Publicado em 2000

Complement plays a minimal role in Sm-p80-mediated protection against Schistosoma mansoni

Por Karmakar, Souvik, Zhang, Weidong, Ahmad, Gul, Alam, Mayeen U, Winn, Richard, Torben, Workineh, Le, Loc, Tillery, Kory A, Siddiqui, Afzal A
Publicado em 2014

Protective and antifecundity effects of Sm-p80 based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model

Por Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Damian, Raymond T., Wolf, Roman F., White, Gary L., Chavez-Suarez, Maria, Kennedy, Ronald C., Siddiqui, Afzal A.
Publicado em 2009

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

Por Rojo, Juan U., Melkus, Michael W., Kottapalli, Kameswara Rao, Okiya, Oscar E., Sudduth, Justin, Zhang, Weidong, Molehin, Adebayo J., Carter, Darrick, Siddiqui, Afzal A.
Publicado no PLoS One (2017)

Induction of Protective Immunity against Schistosoma mansoni via DNA Priming and Boosting with the Large Subunit of Calpain (Sm-p80): Adjuvant Effects of Granulocyte-Macrophage Col...

Por Siddiqui, Afzal A., Phillips, Troy, Charest, Hugues, Podesta, Ron B., Quinlin, Martha L., Pinkston, Justin R., Lloyd, Jenny D., Paz, Michelle, Villalovos, Rachael M., Pompa, Janet
Publicado em 2003

Sm-p80 based DNA vaccine protects baboons against Schistosoma mansoni infection to comparable levels achieved by the irradiated cercarial vaccine

Por Zhang, Weidong, Ahmad1, Gul, Torben, Workineh, Noor, Zahid, Le, Loc, Damian, Raymond T., Wolf, Roman F., White, Gary L., Chavez-Suarez, Maria, Podesta, Ronald B., Kennedy, Ronald C., Siddiqui, Afzal A.
Publicado em 2010

Preclinical Prophylactic Efficacy Testing of Sm-p80–Based Vaccine in a Nonhuman Primate Model of Schistosoma mansoni Infection and Immunoglobulin G and E Responses to Sm-p80 in Hum...

Por Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Ahrorov, Afzal, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Mwinzi, Pauline N. M., Ganley-Leal, Lisa, Kennedy, Ronald C., Siddiqui, Afzal A.
Publicado em 2011

Cross-species protection: Schistosoma mansoni Sm-p80 vaccine confers protection against Schistosoma haematobium in hamsters and baboons

Por Karmakar, Souvik, Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Alam, Mayeen U., Le, Loc, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Carter, Darrick, Reed, Steve G., Siddiqui, Afzal A.
Publicado em 2014

Use of an Sm-p80–Based Therapeutic Vaccine to Kill Established Adult Schistosome Parasites in Chronically Infected Baboons

Por Karmakar, Souvik, Zhang, Weidong, Ahmad, Gul, Torben, Workineh, Alam, Mayeen U., Le, Loc, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Carter, Darrick, Reed, Steven G., Siddiqui, Afzal A.
Publicado em 2014