Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

Schistosomiasis is a neglected parasitic disease of major public health concern as it affects over 250 million people in developing countries. Currently there is no licensed vaccine available against schistosomiasis. The Schistosoma mansoni calpain protein, Sm-p80, is a leading vaccine candidate now...

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Publicat a:PLoS One
Autors principals: Rojo, Juan U., Melkus, Michael W., Kottapalli, Kameswara Rao, Okiya, Oscar E., Sudduth, Justin, Zhang, Weidong, Molehin, Adebayo J., Carter, Darrick, Siddiqui, Afzal A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305113/
https://ncbi.nlm.nih.gov/pubmed/28192534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171677
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