Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

Schistosomiasis is a neglected parasitic disease of major public health concern as it affects over 250 million people in developing countries. Currently there is no licensed vaccine available against schistosomiasis. The Schistosoma mansoni calpain protein, Sm-p80, is a leading vaccine candidate now...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Rojo, Juan U., Melkus, Michael W., Kottapalli, Kameswara Rao, Okiya, Oscar E., Sudduth, Justin, Zhang, Weidong, Molehin, Adebayo J., Carter, Darrick, Siddiqui, Afzal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305113/
https://ncbi.nlm.nih.gov/pubmed/28192534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171677
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