Preclinical Prophylactic Efficacy Testing of Sm-p80–Based Vaccine in a Nonhuman Primate Model of Schistosoma mansoni Infection and Immunoglobulin G and E Responses to Sm-p80 in Human Serum Samples From an Area Where Schistosomiasis Is Endemic

The prophylactic efficacy of a schistosome antigen (Sm-p80) was tested in a nonhuman primate model, the baboon. Using a total of 28 baboons, different vaccination strategies were used including recombinant Sm-p80 protein formulated in Toll-like receptor 7 and Toll-like receptor 9 agonists, and DNA p...

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Detalhes bibliográficos
Main Authors: Ahmad, Gul, Zhang, Weidong, Torben, Workineh, Ahrorov, Afzal, Damian, Raymond T., Wolf, Roman F., White, Gary L., Carey, David W., Mwinzi, Pauline N. M., Ganley-Leal, Lisa, Kennedy, Ronald C., Siddiqui, Afzal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182311/
https://ncbi.nlm.nih.gov/pubmed/21921206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir545
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