Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile

Por Sundriyal, Amit, Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado em 2009

Cwp84, a Clostridium difficile cysteine protease, exhibits conformational flexibility in the absence of its propeptide

Por Bradshaw, William J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no Acta Crystallogr F Struct Biol Commun (2015)

Structure and function of a Clostridium difficile sortase enzyme

Por Chambers, Christopher J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no Sci Rep (2015)

The structure of the S-layer of Clostridium difficile

Por Bradshaw, William J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no J Cell Commun Signal (2017)

Expression, purification, crystallization and preliminary crystallographic analysis of a putative Clostridium difficile surface protein Cwp19

Por Kirby, Jonathan M., Thiyagarajan, Nethaji, Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado em 2011

Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase

Por Holbourn, Kenneth P., Sutton, J. Mark, Evans, Hazel R., Shone, Clifford C., Acharya, K. Ravi
Publicado em 2005

Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro

Por Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no FEBS J (2017)

The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile

Por Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no FEBS J (2017)

Cwp84, a Surface-associated Cysteine Protease, Plays a Role in the Maturation of the Surface Layer of Clostridium difficile

Por Kirby, Jonathan M., Ahern, Helen, Roberts, April K., Kumar, Vivek, Freeman, Zoe, Acharya, K. Ravi, Shone, Clifford C.
Publicado em 2009

Functional significance of active site residues in the enzymatic component of the Clostridium difficile binary toxin

Por Davies, Abigail H., McGlashan, Joanna, Posner, Mareike G., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado no Biochem Biophys Rep (2016)

The structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein from Clostridium difficile

Por Bradshaw, William J., Kirby, Jonathan M., Thiyagarajan, Nethaji, Chambers, Christopher J., Davies, Abigail H., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Publicado em 2014

High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection again...

Por Monaghan, Tanya M, Negm, Ola H, MacKenzie, Brendon, Hamed, Mohamed R, Shone, Clifford C, Humphreys, David P, Acharya, K Ravi, Wilcox, Mark H
Publicado no Clin Exp Gastroenterol (2017)

A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

Por Azarnia Tehran, Domenico, Zanetti, Giulia, Leka, Oneda, Lista, Florigio, Fillo, Silvia, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare, Paradisi, Cristina, Mattarei, Andrea, Pirazzini, Marco
Publicado no Sci Rep (2015)

Inhibition of Vesicular Secretion in Both Neuronal and Nonneuronal Cells by a Retargeted Endopeptidase Derivative of Clostridium botulinum Neurotoxin Type A

Por Chaddock, John A., Purkiss, John R., Friis, Lorna M., Broadbridge, Janice D., Duggan, Michael J., Fooks, Sarah J., Shone, Clifford C., Quinn, Conrad P., Foster, Keith A.
Publicado em 2000

Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis

Por Negm, Ola H., Hamed, Mohamed R., Dilnot, Elizabeth M., Shone, Clifford C., Marszalowska, Izabela, Lynch, Mark, Loscher, Christine E., Edwards, Laura J., Tighe, Patrick J., Wilcox, Mark H., Monaghan, Tanya M.
Publicado no Clin Vaccine Immunol (2015)