High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection

OBJECTIVES: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare. The aim of this study was to compare the prevalence of binding C. difficile toxin-specific immunoglobulin (Ig)A, IgG...

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Detalhes bibliográficos
Publicado no:Clin Exp Gastroenterol
Main Authors: Monaghan, Tanya M, Negm, Ola H, MacKenzie, Brendon, Hamed, Mohamed R, Shone, Clifford C, Humphreys, David P, Acharya, K Ravi, Wilcox, Mark H
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525456/
https://ncbi.nlm.nih.gov/pubmed/28765714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S133939
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