High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection

OBJECTIVES: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare. The aim of this study was to compare the prevalence of binding C. difficile toxin-specific immunoglobulin (Ig)A, IgG...

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Publicado en:Clin Exp Gastroenterol
Autores principales: Monaghan, Tanya M, Negm, Ola H, MacKenzie, Brendon, Hamed, Mohamed R, Shone, Clifford C, Humphreys, David P, Acharya, K Ravi, Wilcox, Mark H
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525456/
https://ncbi.nlm.nih.gov/pubmed/28765714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S133939
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