Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy

Por Fan, Xiaozhou, Quezada, Sergio A., Sepulveda, Manuel A., Sharma, Padmanee, Allison, James P.
Publicado em 2014

Changes in Replication, Nuclear Location, and Expression of the Igh Locus after Fusion of a Pre-B Cell Line with a T Cell Line

Por Zhou, Jie, Saleque, Shireen, Ermakova, Olga, Sepulveda, Manuel A., Yang, Qiaoxin, Eckhardt, Laurel A., Schildkraut, Carl L., Birshtein, Barbara K.
Publicado em 2005

The DNA methylation profile of activated human natural killer cells

Por Wiencke, John. K., Butler, Rondi, Hsuang, George, Eliot, Melissa, Kim, Stephanie, Sepulveda, Manuel A., Siegel, Derick, Houseman, E. Andres, Kelsey, Karl T.
Publicado no Epigenetics (2016)

Chronic Inflammatory Liver Disease in Mice Expressing a CD28-specific Ligand

Por Corse, Emily, Gottschalk, Rachel A., Park, Joon Seok, Sepulveda, Manuel A., Loke, P’ng, Sullivan, Timothy J., Johnson, Linda K., Allison, James P.
Publicado no J Immunol (2012)

Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody

Por Jarantow, Stephen W., Bushey, Barbara S., Pardinas, Jose R., Boakye, Ken, Lacy, Eilyn R., Sanders, Renouard, Sepulveda, Manuel A., Moores, Sheri L., Chiu, Mark L.
Publicado no J Biol Chem (2015)

Chromatin Architecture near a Potential 3′ End of the Igh Locus Involves Modular Regulation of Histone Modifications during B-Cell Development and In Vivo Occupancy at CTCF Sites

Por Garrett, Francine E., Emelyanov, Alexander V., Sepulveda, Manuel A., Flanagan, Patrick, Volpi, Sabrina, Li, Fubin, Loukinov, Dmitry, Eckhardt, Laurel A., Lobanenkov, Victor V., Birshtein, Barbara K.
Publicado em 2005

A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription

Por Barlev, Nickolai A., Emelyanov, Alexander V., Castagnino, Paola, Zegerman, Philip, Bannister, Andrew J., Sepulveda, Manuel A., Robert, Flavie, Tora, Laszlo, Kouzarides, Tony, Birshtein, Barbara K., Berger, Shelley L.
Publicado em 2003

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Por Simpson, Tyler R., Li, Fubin, Montalvo-Ortiz, Welby, Sepulveda, Manuel A., Bergerhoff, Katharina, Arce, Frederick, Roddie, Claire, Henry, Jake Y., Yagita, Hideo, Wolchok, Jedd D., Peggs, Karl S., Ravetch, Jeffrey V., Allison, James P., Quezada, Sergio A.
Publicado em 2013

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

Por Gao, Jianjun, Ward, John F, Pettaway, Curtis A, Shi, Lewis Z, Subudhi, Sumit K, Vence, Luis M, Zhao, Hao, Chen, Jianfeng, Chen, Hong, Efstathiou, Eleni, Troncoso, Patricia, Allison, James P, Logothetis, Christopher J, Wistuba, Ignacio I, Sepulveda, Manuel A, Sun, Jingjing, Wargo, Jennifer, Blando, Jorge, Sharma, Padmanee
Publicado no Nat Med (2017)

Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors

Por Kumar, Vinit, Donthireddy, Laxminarasimha, Marvel, Douglas, Condamine, Thomas, Wang, Fang, Lavilla-Alonso, Sergio, Hashimoto, Ayumi, Vonteddu, Prashanthi, Behera, Reeti, Goins, Marlee A, Mulligan, Charles, Nam, Brian, Hockstein, Neil, Denstman, Fred, Shakamuri, Shanti, Speicher, David W., Weeraratna, Ashani T., Chao, Timothy, Vonderheide, Robert H., Languino, Lucia R., Ordentlich, Peter, Liu, Qin, Xu, Xiaowei, Lo, Albert, Puré, Ellen, Zhang, Chunsheng, Loboda, Andrey, Sepulveda, Manuel A, Snyder, Linda A, Gabrilovich, Dmitry
Publicado no Cancer Cell (2017)

Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients

Por Condamine, Thomas, Dominguez, George A., Youn, Je-In, Kossenkov, Andrew V., Mony, Sridevi, Alicea-Torres, Kevin, Tcyganov, Evgenii, Hashimoto, Ayumi, Nefedova, Yulia, Lin, Cindy, Partlova, Simona, Garfall, Alfred, Vogl, Dan T., Xu, Xiaowei, Knight, Stella C., Malietzis, George, Lee, Gui Han, Eruslanov, Evgeniy, Albelda, Steven M., Wang, Xianwei, Mehta, Jawahar L., Bewtra, Meenakshi, Rustgi, Anil, Hockstein, Neil, Witt, Robert, Masters, Gregory, Nam, Brian, Smirnov, Denis, Sepulveda, Manuel A., Gabrilovich, Dmitry I.
Publicado no Sci Immunol (2016)