Melanoma reactive TCR-modified T cells generated without activation retain a less differentiated phenotype and mediate a superior in vivo response

by Wang, Siao-Yi, Moore, Tamson V., Dalheim, Annika V., Scurti, Gina M., Nishimura, Michael I.
Published in Sci Rep (2021)

Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells

by Spear, Timothy T., Wang, Yuan, Foley, Kendra C., Murray, David C., Scurti, Gina M., Simms, Patricia E., Garrett-Mayer, Elizabeth, Hellman, Lance M., Baker, Brian M., Nishimura, Michael I.
Published in Cancer Immunol Immunother (2017)

TCR gene-modified T cells can efficiently treat established hepatitis C-associated hepatocellular carcinoma tumors

by Spear, Timothy T., Callender, Glenda G., Roszkowski, Jeffrey J., Moxley, Kelly M., Simms, Patricia E., Foley, Kendra C., Murray, David C., Scurti, Gina M., Li, Mingli, Thomas, Justin T., Langerman, Alexander, Garrett-Mayer, Elizabeth, Zhang, Yi, Nishimura, Michael I.
Published in Cancer Immunol Immunother (2016)

Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells

by Rubinstein, Mark P., Su, Ee Wern, Suriano, Samantha, Cloud, Colleen A., Andrijauskaite, Kristina, Kesarwani, Pravin, Schwartz, Kristina M., Williams, Katelyn M., Johnson, C. Bryce, Li, Mingli, Scurti, Gina M., Salem, Mohamed L., Paulos, Chrystal M., Garrett-Mayer, Elizabeth, Mehrotra, Shikhar, Cole, David J.
Published in Cancer Immunol Immunother (2015)

Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability

by Spear, Timothy T., Riley, Timothy P., Lyons, Gretchen E., Callender, Glenda G., Roszkowski, Jeffrey J., Wang, Yuan, Simms, Patricia E., Scurti, Gina M., Foley, Kendra C., Murray, David C., Hellman, Lance M., McMahan, Rachel H., Iwashima, Makio, Garrett-Mayer, Elizabeth, Rosen, Hugo R., Baker, Brian M., Nishimura, Michael I.
Published in J Leukoc Biol (2016)

HDAC inhibition prevents transgene expression downregulation and loss-of-function in T-cell-receptor-transduced T cells

by Moore, Tamson V., Scurti, Gina M., DeJong, Matthew, Wang, Siao-Yi, Dalheim, Annika V., Wagner, Courtney R., Hutchens, Kelli A., Speiser, Jodi J., Godellas, Constantine V., Fountain, Chris, Fleser, Jessica, Moudgil, Tarsem, Thomas, Mallory, Murray, David, Curti, Brendan D., Clark, Joseph I., Fox, Bernard A., Nishimura, Michael I.
Published in Mol Ther Oncolytics (2021)

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells

by Moore, Tamson, Wagner, Courtney Regan, Scurti, Gina M., Hutchens, Kelli A., Godellas, Constantine, Clark, Ann Lau, Kolawole, Elizabeth Motunrayo, Hellman, Lance M., Singh, Nishant K., Huyke, Fernando A., Wang, Siao-Yi, Calabrese, Kelly M., Embree, Heather D., Orentas, Rimas, Shirai, Keisuke, Dellacecca, Emilia, Garrett-Mayer, Elizabeth, Li, Mingli, Eby, Jonathan M., Stiff, Patrick J., Evavold, Brian D., Baker, Brian M., Le Poole, I. Caroline, Dropulic, Boro, Clark, Joseph I., Nishimura, Michael I.
Published in Cancer Immunol Immunother (2017)