Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells

Por Blijlevens, Maxime, Komor, Malgorzata A., Sciarrillo, Rocco, Smit, Egbert F., Fijneman, Remond J. A., van Beusechem, Victor W.
Publicado no Int J Mol Sci (2020)

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models

Por Sciarrillo, Rocco, Wojtuszkiewicz, Anna, Kooi, Irsan E., Gómez, Valentina E., Boggi, Ugo, Jansen, Gerrit, Kaspers, Gert-Jan, Cloos, Jacqueline, Giovannetti, Elisa
Publicado no J Vis Exp (2016)

Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation

Por Sciarrillo, Rocco, Wojtuszkiewicz, Anna, Kooi, Irsan E., Leon, Leticia G., Sonneveld, Edwin, Kuiper, Roland P., Jansen, Gerrit, Giovannetti, Elisa, Kaspers, Gertjan J.L., Cloos, Jacqueline
Publicado no Cancers (Basel) (2020)

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Por Wojtuszkiewicz, Anna, Assaraf, Yehuda G., Hoekstra, Mirthe, Sciarrillo, Rocco, Jansen, Gerrit, Peters, Godefridus J., Pieters, Rob, Sonneveld, Edwin, Escherich, Gabriele, Kaspers, Gertjan J.L., Cloos, Jacqueline
Publicado no Haematologica (2016)

NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor

Por Galvani, Elena, Sun, Jing, Leon, Leticia G., Sciarrillo, Rocco, Narayan, Ravi S., Tjin Tham Sjin, Robert, Lee, Kwangho, Ohashi, Kadoaki, Heideman, Daniëlle A.M., Alfieri, Roberta R., Heynen, Guus J., Bernards, René, Smit, Egbert F., Pao, William, Peters, Godefridus J., Giovannetti, Elisa
Publicado no Oncotarget (2015)

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

Por Cavazzoni, Andrea, La Monica, Silvia, Alfieri, Roberta, Ravelli, Andrea, Van Der Steen, Nele, Sciarrillo, Rocco, Madeddu, Denise, Lagrasta, Costanza Anna Maria, Quaini, Federico, Bonelli, Mara, Fumarola, Claudia, Cretella, Daniele, Digiacomo, Graziana, Tiseo, Marcello, Peters, Godefridus J., Ardizzoni, Andrea, Petronini, Pier Giorgio, Giovannetti, Elisa
Publicado no Oncotarget (2017)

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

Por Sciarrillo, Rocco, Wojtuszkiewicz, Anna, El Hassouni, Btissame, Funel, Niccola, Gandellini, Paolo, Lagerweij, Tonny, Buonamici, Silvia, Blijlevens, Maxime, Zeeuw van der Laan, Eveline A., Zaffaroni, Nadia, Deraco, Marcello, Kusamura, Shigeki, Würdinger, Tom, Peters, Godefridus J., Molthoff, Carla F.M., Jansen, Gerrit, Kaspers, Gertjan J.L., Cloos, Jacqueline, Giovannetti, Elisa
Publicado no EBioMedicine (2018)

Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds

Por Li Petri, Giovanna, El Hassouni, Btissame, Sciarrillo, Rocco, Funel, Niccola, Mantini, Giulia, Zeeuw van der Laan, Eveline A., Cascioferro, Stella, Avan, Amir, Zucali, Paolo Andrea, Zaffaroni, Nadia, Lagerweij, Tonny, Parrino, Barbara, Smid, Kees, Deraco, Marcello, Granchi, Carlotta, Braczko, Alicja, Smolenski, Ryszard T., Matherly, Larry H., Jansen, Gerrit, Assaraf, Yehuda G., Diana, Patrizia, Cloos, Jacqueline, Peters, Godefridus J., Minutolo, Filippo, Giovannetti, Elisa
Publicado no Br J Cancer (2020)