Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models

Drug resistance remains a major problem in the treatment of cancer for both hematological malignancies and solid tumors. Intrinsic or acquired resistance can be caused by a range of mechanisms, including increased drug elimination, decreased drug uptake, drug inactivation and alterations of drug tar...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Sciarrillo, Rocco, Wojtuszkiewicz, Anna, Kooi, Irsan E., Gómez, Valentina E., Boggi, Ugo, Jansen, Gerrit, Kaspers, Gert-Jan, Cloos, Jacqueline, Giovannetti, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226372/
https://ncbi.nlm.nih.gov/pubmed/28060337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54714
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