Testing for differentially expressed genetic pathways with single-subject N-of-1 data in the presence of inter-gene correlation

par Schissler, A. Grant, Piegorsch, Walter W., Lussier, Yves A.
Publié dans Stat Methods Med Res (2017)

Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses()

par Zaim, Samir Rachid, Li, Qike, Schissler, A. Grant, Lussier, Yves A.
Publié dans Pac Symp Biocomput (2018)

Autologistic models for benchmark risk or vulnerability assessment of urban terrorism outcomes

par Liu, Jingyu, Piegorsch, Walter W., Schissler, A. Grant, Cutter, Susan L.
Publié dans J R Stat Soc Ser A Stat Soc (2017)

NBIA: a network-based integrative analysis framework – applied to pathway analysis

par Nguyen, Tin, Shafi, Adib, Nguyen, Tuan-Minh, Schissler, A. Grant, Draghici, Sorin
Publié dans Sci Rep (2020)

Developing a ‘personalome’ for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes

par Vitali, Francesca, Li, Qike, Schissler, A Grant, Berghout, Joanne, Kenost, Colleen, Lussier, Yves A
Publié dans Brief Bioinform (2017)

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

par Schissler, A. Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publié dans Bioinformatics (2015)

kMEn: analyzing noisy and bidirectional transcriptional pathway responses in single subjects

par Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Kenost, Colleen, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publié dans J Biomed Inform (2016)

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

par Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Achour, Ikbel, Kenost, Colleen, Berghout, Joanne, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publié dans BMC Med Genomics (2017)

Analysis of aggregated cell–cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

par Schissler, A. Grant, Li, Qike, Chen, James L., Kenost, Colleen, Achour, Ikbel, Billheimer, D. Dean, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publié dans Bioinformatics (2016)

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

par Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Schissler, A Grant, Li, Qike, Kenost, Colleen, Li, Jianrong, Shang, Yuan, Bosco, Anthony, Saner, Donald, Halonen, Marilyn J, Jackson, Daniel J, Li, Haiquan, Martinez, Fernando D, Lussier, Yves A
Publié dans J Am Med Inform Assoc (2017)