Testing for differentially expressed genetic pathways with single-subject N-of-1 data in the presence of inter-gene correlation

por Schissler, A. Grant, Piegorsch, Walter W., Lussier, Yves A.
Publicado en Stat Methods Med Res (2017)

Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses()

por Zaim, Samir Rachid, Li, Qike, Schissler, A. Grant, Lussier, Yves A.
Publicado en Pac Symp Biocomput (2018)

Autologistic models for benchmark risk or vulnerability assessment of urban terrorism outcomes

por Liu, Jingyu, Piegorsch, Walter W., Schissler, A. Grant, Cutter, Susan L.
Publicado en J R Stat Soc Ser A Stat Soc (2017)

NBIA: a network-based integrative analysis framework – applied to pathway analysis

por Nguyen, Tin, Shafi, Adib, Nguyen, Tuan-Minh, Schissler, A. Grant, Draghici, Sorin
Publicado en Sci Rep (2020)

Developing a ‘personalome’ for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes

por Vitali, Francesca, Li, Qike, Schissler, A Grant, Berghout, Joanne, Kenost, Colleen, Lussier, Yves A
Publicado en Brief Bioinform (2017)

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

por Schissler, A. Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado en Bioinformatics (2015)

kMEn: analyzing noisy and bidirectional transcriptional pathway responses in single subjects

por Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Kenost, Colleen, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publicado en J Biomed Inform (2016)

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

por Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Achour, Ikbel, Kenost, Colleen, Berghout, Joanne, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publicado en BMC Med Genomics (2017)

Analysis of aggregated cell–cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

por Schissler, A. Grant, Li, Qike, Chen, James L., Kenost, Colleen, Achour, Ikbel, Billheimer, D. Dean, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado en Bioinformatics (2016)

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

por Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Schissler, A Grant, Li, Qike, Kenost, Colleen, Li, Jianrong, Shang, Yuan, Bosco, Anthony, Saner, Donald, Halonen, Marilyn J, Jackson, Daniel J, Li, Haiquan, Martinez, Fernando D, Lussier, Yves A
Publicado en J Am Med Inform Assoc (2017)