NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma

Por Sato, Tatsuhiro, Sekido, Yoshitaka
Publicado no Int J Mol Sci (2018)

Characterization of the Rheb-mTOR Signaling Pathway in Mammalian Cells: Constitutive Active Mutants of Rheb and mTOR

Por Sato, Tatsuhiro, Umetsu, Akiko, Tamanoi, Fuyuhiko
Publicado em 2008

Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin

Por Nakashima, Akio, Sato, Tatsuhiro, Tamanoi, Fuyuhiko
Publicado em 2010

Specific Activation of mTORC1 by Rheb G-protein in Vitro Involves Enhanced Recruitment of Its Substrate Protein

Por Sato, Tatsuhiro, Nakashima, Akio, Guo, Lea, Tamanoi, Fuyuhiko
Publicado em 2009

Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells

Por Urano, Jun, Sato, Tatsuhiro, Matsuo, Tomohiko, Otsubo, Yoko, Yamamoto, Masayuki, Tamanoi, Fuyuhiko
Publicado em 2007

Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase

Por Nakashima, Akio, Otsubo, Yoko, Yamashita, Akira, Sato, Tatsuhiro, Yamamoto, Masayuki, Tamanoi, Fuyuhiko
Publicado em 2012

Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma

Por Shigeeda, Wataru, Shibazaki, Masahiko, Yasuhira, Shinji, Masuda, Tomoyuki, Tanita, Tatsuo, Kaneko, Yuka, Sato, Tatsuhiro, Sekido, Yoshitaka, Maesawa, Chihaya
Publicado no Oncotarget (2017)

Rheb Protein Binds CAD (Carbamoyl-phosphate Synthetase 2, Aspartate Transcarbamoylase, and Dihydroorotase) Protein in a GTP- and Effector Domain-dependent Manner and Influences Its...

Por Sato, Tatsuhiro, Akasu, Hitomi, Shimono, Wataru, Matsu, Chisa, Fujiwara, Yuki, Shibagaki, Yoshio, Heard, Jeffrey J., Tamanoi, Fuyuhiko, Hattori, Seisuke
Publicado no J Biol Chem (2015)

Exon skipping causes atypical phenotypes associated with a loss-of-function mutation in FLNA by restoring its protein function

Por Oda, Hirotsugu, Sato, Tatsuhiro, Kunishima, Shinji, Nakagawa, Kenji, Izawa, Kazushi, Hiejima, Eitaro, Kawai, Tomoki, Yasumi, Takahiro, Doi, Hiraku, Katamura, Kenji, Numabe, Hironao, Okamoto, Shinya, Nakase, Hiroshi, Hijikata, Atsushi, Ohara, Osamu, Suzuki, Hidenori, Morisaki, Hiroko, Morisaki, Takayuki, Nunoi, Hiroyuki, Hattori, Seisuke, Nishikomori, Ryuta, Heike, Toshio
Publicado no Eur J Hum Genet (2016)