Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells

Por Hollomon, Mario G, Gordon, Nancy, Santiago-O’Farrill, Janice M, Kleinerman, Eugenie S
Publicado em 2013

Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy

Por Santiago-O’Farrill, Janice M., Kleinerman, Eugenie S., Hollomon, Mario G., Livingston, Andrew, Wang, Wei-Lien, Tsai, Jen-Wei, Gordon, Nancy B.
Publicado no Oncotarget (2017)

A novel compound ARN-3236 inhibits Salt Inducible Kinase 2 and sensitizes ovarian cancer cell lines and xenografts to paclitaxel

Por Zhou, Jinhua, Alfraidi, Albandri, Zhang, Shu, Santiago-O’Farrill, Janice M., Yerramreddy, Venkata Krishna Reddy, Alsaadi, Abdulkhaliq, Ahmed, Ahmed A., Yang, Hailing, Liu, Jinsong, Mao, Weiqun, Wang, Yan, Takemori, Hiroshi, Vankayalapati, Hariprasad, Lu, Zhen, Bast, Robert C.
Publicado no Clin Cancer Res (2016)

Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to ALK inhibition

Por Blessing, Alicia M., Santiago-O’Farrill, Janice M., Mao, Weiqun, Pang, Lan, Ning, Jing, Pak, Daewoo, Bollu, Lakshmi Reddy, Rask, Philip, Iles, LaKesla, Tran, Samantha, Elmir, Ezzeddine, Bartholomeusz, Geoffrey, Langley, Robert, Lu, Zhen, Bast, Robert C.
Publicado no Cancer (2020)

Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

Por Irwin, Mary E., Nelson, Laura D., Santiago-O’Farrill, Janice M., Knouse, Phillip D., Miller, Claudia P., Palla, Shana L., Siwak, Doris R., Mills, Gordon B., Estrov, Zeev, Li, Shulin, Kornblau, Steven M., Hughes, Dennis P., Chandra, Joya
Publicado em 2013

Poly adenosine diphosphate ribose polymerase inhibitors (PARPi) induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts and PDX models

Por Santiago-O’Farrill, Janice M., Weroha, S. John, Hou, Xiaonan, Oberg, Ann L., Heinzen, Ethan P., Maurer, Matthew J., Pang, Lan, Rask, Philip, Amaravadi, Ravi K., Becker, Sarah E., Romero, Ignacio, Rubió, M. Jesús, Matias-Guiu, X., Santacana, Maria, Llombart-Cussac, Antonio, Poveda, Andrés, Lu, Zhen, Bast, Robert C.
Publicado no Cancer (2019)