Glucocerebrosidase Mutations and Synucleinopathies. Potential Role of Sterylglucosides and Relevance of Studying Both GBA1 and GBA2 Genes

Por Franco, Rafael, Sánchez-Arias, Juan A., Navarro, Gemma, Lanciego, José L.
Publicado no Front Neuroanat (2018)

A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice

Por Cuadrado-Tejedor, Mar, Garcia-Barroso, Carolina, Sánchez-Arias, Juan A, Rabal, Obdulia, Pérez-González, Marta, Mederos, Sara, Ugarte, Ana, Franco, Rafael, Segura, Victor, Perea, Gertrudis, Oyarzabal, Julen, Garcia-Osta, Ana
Publicado no Neuropsychopharmacology (2017)

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage

Por Rodríguez, José A., Sobrino, Tomás, López‐Arias, Esteban, Ugarte, Ana, Sánchez‐Arias, Juan A., Vieites‐Prado, Alba, de Miguel, Irene, Oyarzabal, Julen, Páramo, José A., Campos, Francisco, Orbe, Josune, Castillo, José
Publicado no J Am Heart Assoc (2017)

Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

Por de Miguel, Irene, Orbe, Josune, Sánchez-Arias, Juan A., Rodríguez, José A., Salicio, Agustina, Rabal, Obdulia, Belzunce, Miriam, Sáez, Elena, Xu, Musheng, Wu, Wei, Tan, Haizhong, Ma, Hongyu, Páramo, José A., Oyarzabal, Julen
Publicado no ACS Med Chem Lett (2018)

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

Por San José-Enériz, Edurne, Agirre, Xabier, Rabal, Obdulia, Vilas-Zornoza, Amaia, Sanchez-Arias, Juan A., Miranda, Estibaliz, Ugarte, Ana, Roa, Sergio, Paiva, Bruno, Estella-Hermoso de Mendoza, Ander, Alvarez, Rosa María, Casares, Noelia, Segura, Victor, Martín-Subero, José I., Ogi, François-Xavier, Soule, Pierre, Santiveri, Clara M., Campos-Olivas, Ramón, Castellano, Giancarlo, de Barrena, Maite Garcia Fernandez, Rodriguez-Madoz, Juan Roberto, García-Barchino, Maria José, Lasarte, Juan Jose, Avila, Matias A, Martinez-Climent, Jose Angel, Oyarzabal, Julen, Prosper, Felipe
Publicado no Nat Commun (2017)