Castration-Resistant Prostate Cancer: Targeted Therapies and Individualized Treatment

Por Aggarwal, Rahul, Ryan, Charles J.
Publicado em 2011

DNA Repair Deficiency Is Common in Advanced Prostate Cancer: New Therapeutic Opportunities

Por Dhawan, Mallika, Ryan, Charles J., Ashworth, Alan
Publicado no Oncologist (2016)

Bone-Targeting Radiopharmaceuticals for the Treatment of Bone-Metastatic Castration-Resistant Prostate Cancer: Exploring the Implications of New Data

Por Ryan, Charles J., Saylor, Philip J., Everly, Jason J., Sartor, Oliver
Publicado em 2014

Abiraterone acetate and prednisone in chemotherapy-naïve prostate cancer patients: rationale, evidence and clinical utility

Por Crawford, E. David, Shore, Neal D., Petrylak, Daniel P., Higano, Celestia S., Ryan, Charles J.
Publicado no Ther Adv Med Oncol (2017)

A Phase I Study of Abiraterone Acetate Combined with BEZ235, a Dual PI3K/mTOR Inhibitor, in Metastatic Castration Resistant Prostate Cancer

Por Wei, Xiao X., Hsieh, Andrew C., Kim, Won, Friedlander, Terence, Lin, Amy M., Louttit, Mirela, Ryan, Charles J.
Publicado no Oncologist (2017)

Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer

Por Magbanua Mark, Sosa Eduardo V, Scott Janet H, Simko Jeff, Collins Colin, Pinkel Dan, Ryan Charles J, Park John W
Publicado em 2012-02-01

Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer

Por Magbanua, Mark Jesus M, Sosa, Eduardo V, Scott, Janet H, Simko, Jeff, Collins, Colin, Pinkel, Dan, Ryan, Charles J, Park, John W
Publicado em 2012

Serum Androgens As Prognostic Biomarkers in Castration-Resistant Prostate Cancer: Results From an Analysis of a Randomized Phase III Trial

Por Ryan, Charles J., Molina, Arturo, Li, Jinhui, Kheoh, Thian, Small, Eric J., Haqq, Christopher M., Grant, Russell P., de Bono, Johann S., Scher, Howard I.
Publicado no J Clin Oncol (2013)

(68)Ga-PSMA-11 PET Imaging of Response to Androgen Receptor Inhibition: First Human Experience

Por Hope, Thomas A., Truillet, Charles, Ehman, Eric C., Afshar-Oromieh, Ali, Aggarwal, Rahul, Ryan, Charles J., Carroll, Peter R., Small, Eric J., Evans, Michael J.
Publicado no J Nucl Med (2017)

Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: A randomized phase II trial by the Prostate Cancer Clinical Trials Co...

Por Bradley, Deborah A., Daignault, Stephanie, Ryan, Charles J., DiPaola, Robert S., Smith, David C., Small, Eric, Gross, Mitchell E., Stein, Mark N., Chen, Alice, Hussain, Maha
Publicado em 2010

Efficacy and Safety of Abiraterone Acetate in Elderly (≥75 Years) Chemotherapy-Naïve Patients with Metastatic Castration-Resistant Prostate Cancer

Por Smith, Matthew R., Rathkopf, Dana E., Mulders, Peter. F.A., Carles, Joan, Van Poppel, Hendrik, Li, Jinhui, Kheoh, Thian, Griffin, Thomas W., Molina, Arturo, Ryan, Charles J.
Publicado no J Urol (2015)

A Novel Androgen Receptor Amino Terminal Region Reveals Two Classes of Amino/Carboxyl Interaction-Deficient Variants with Divergent Capacity to Activate Responsive Sites in Chromat...

Por Need, Eleanor F., Scher, Howard I., Peters, Amelia A., Moore, Nicole L., Cheong, Albert, Ryan, Charles J., Wittert, Gary A., Marshall, Villis R., Tilley, Wayne D., Buchanan, Grant
Publicado em 2009

Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconaz...

Por Ryan, Charles J., Smith, Matthew R., Fong, Lawrence, Rosenberg, Jonathan E., Kantoff, Philip, Raynaud, Florence, Martins, Vanessa, Lee, Gloria, Kheoh, Thian, Kim, Jennifer, Molina, Arturo, Small, Eric J.
Publicado em 2010

Prostate Cancer Academy 2016: Presentation summaries

Por Crawford, E. David, Albala, David M., Wysocki, James S., Lepor, Herbert, Ross, Ashley E., Finkelstein, Steven E., Keane, Thomas, Freedland, Stephen, Harris, Richard, Shore, Neal D., Ryan, Charles J.
Publicado no Rev Urol (2016)

A non-comparative randomized phase II study of two doses of ATN-224, a copper/zinc superoxide dismutase inhibitor, in patients with biochemically recurrent hormone-naïve prostate c...

Por Lin, Jianqing, Zahurak, Marianna, Beer, Tomasz M., Ryan, Charles. J., Wilding, George, Mathew, Paul, Morris, Michael, Callahan, Jennifer. A., Gordon, Gilad, Reich, Steven D., Carducci, Michael A., Antonarakis, Emmanuel S.
Publicado em 2011

Phase II Study of Abiraterone Acetate Plus Prednisone in Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer Demonstrating Radiographic Flare Discordant With Serolog...

Por Ryan, Charles J., Shah, Shreya, Efstathiou, Eleni, Smith, Matthew R., Taplin, Mary-Ellen, Bubley, Glenn J., Logothetis, Christopher J., Kheoh, Thian, Kilian, Christine, Haqq, Chris, Molina, Arturo, Small, Eric J.
Publicado em 2011

Phase I Study of Ixabepilone, Mitoxantrone, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Therapy: A Study...

Por Rosenberg, Jonathan E., Ryan, Charles J., Weinberg, Vivian K., Smith, David C., Hussain, Maha, Beer, Tomasz M., Ryan, Christopher W., Mathew, Paul, Pagliaro, Lance C., Harzstark, Andrea L., Sharib, Jeremy, Small, Eric J.
Publicado em 2009

Randomized Controlled Trial of Early Zoledronic Acid in Men With Castration-Sensitive Prostate Cancer and Bone Metastases: Results of CALGB 90202 (Alliance)

Por Smith, Matthew R., Halabi, Susan, Ryan, Charles J., Hussain, Arif, Vogelzang, Nicholas, Stadler, Walter, Hauke, Ralph J., Monk, J. Paul, Saylor, Philip, Bhoopalam, Nirmala, Saad, Fred, Sanford, Ben, Kelly, W. Kevin, Morris, Michael, Small, Eric J.
Publicado em 2014

Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens

Por Kim, Won, Zhang, Li, Wilton, John H., Fetterly, Gerald, Mohler, James L., Weinberg, Vivian, Morse, Allison, Szmulewitz, Russell, Friedlander, Terence W., Fong, Lawrence, Lin, Amy M., Harzstark, Andrea, Molina, Arturo, Small, Eric J., Ryan, Charles J.
Publicado no Clin Cancer Res (2014)

Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Can...

Por Smith, Matthew R., Antonarakis, Emmanuel S., Ryan, Charles J., Berry, William R., Shore, Neal D., Liu, Glenn, Alumkal, Joshi J., Higano, Celestia S., Maneval, Edna Chow, Bandekar, Rajesh, de Boer, Carla J., Yu, Margaret K., Rathkopf, Dana E.
Publicado no Eur Urol (2016)