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Phase I Study of Ixabepilone, Mitoxantrone, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Therapy: A Study of the Department of Defense Prostate Cancer Clinical Trials Consortium

PURPOSE: Mitoxantrone plus prednisone and ixabepilone each have modest activity as second-line chemotherapy in docetaxel-refractory castration-resistant prostate cancer (CRPC) patients. Clinical noncrossresistance was previously observed. PATIENTS AND METHODS: Metastatic CRPC patients progressing du...

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Detalhes bibliográficos
Main Authors: Rosenberg, Jonathan E., Ryan, Charles J., Weinberg, Vivian K., Smith, David C., Hussain, Maha, Beer, Tomasz M., Ryan, Christopher W., Mathew, Paul, Pagliaro, Lance C., Harzstark, Andrea L., Sharib, Jeremy, Small, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698016/
https://ncbi.nlm.nih.gov/pubmed/19349545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.8002
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