Co-Injection of a Targeted, Reversibly Masked Endosomolytic Polymer Dramatically Improves the Efficacy of Cholesterol-Conjugated Small Interfering RNAs In Vivo

ανά Wong, So C., Klein, Jason J., Hamilton, Holly L., Chu, Qili, Frey, Christina L., Trubetskoy, Vladimir S., Hegge, Julia, Wakefield, Darren, Rozema, David B., Lewis, David L.
Έκδοση 2012

Phosphorylation-specific status of RNAi triggers in pharmacokinetic and biodistribution analyses

ανά Trubetskoy, Vladimir S., Griffin, Jacob B., Nicholas, Anthony L., Nord, Eric M., Xu, Zhao, Peterson, Ryan M., Wooddell, Christine I., Rozema, David B., Wakefield, Darren H., Lewis, David L., Kanner, Steven B.
Τόπος έκδοσης Nucleic Acids Res (2017)

Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

ανά Rozema, David B., Lewis, David L., Wakefield, Darren H., Wong, So C., Klein, Jason J., Roesch, Paula L., Bertin, Stephanie L., Reppen, Tom W., Chu, Qili, Blokhin, Andrei V., Hagstrom, James E., Wolff, Jon A.
Έκδοση 2007

Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection

ανά Wooddell, Christine I, Rozema, David B, Hossbach, Markus, John, Matthias, Hamilton, Holly L, Chu, Qili, Hegge, Julia O, Klein, Jason J, Wakefield, Darren H, Oropeza, Claudia E, Deckert, Jochen, Roehl, Ingo, Jahn-Hofmann, Kerstin, Hadwiger, Philipp, Vornlocher, Hans-Peter, McLachlan, Alan, Lewis, David L
Έκδοση 2013