Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast

Por Roscoe, Benjamin P., Bolon, Daniel N. A.
Publicado em 2014

Analyses of the effects of all ubiquitin point mutants on yeast growth rate

Por Roscoe, Benjamin P., Thayer, Kelly M., Zeldovich, Konstantin B., Fushman, David, Bolon, Daniel N. A.
Publicado em 2013

Viewing Protein Fitness Landscapes Through a Next-Gen Lens

Por Boucher, Jeffrey I., Cote, Pamela, Flynn, Julia, Jiang, Li, Laban, Aneth, Mishra, Parul, Roscoe, Benjamin P., Bolon, Daniel N. A.
Publicado em 2014

Precise therapeutic gene correction by a simple nuclease-induced double-strand break

Por Iyer, Sukanya, Suresh, Sneha, Guo, Dongsheng, Daman, Katelyn, Chen, Jennifer C. J., Liu, Pengpeng, Zieger, Marina, Luk, Kevin, Roscoe, Benjamin P., Mueller, Christian, King, Oliver D., Emerson, Charles P., Wolfe, Scot A.
Publicado no Nature (2019)

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Por Wu, Yuxuan, Zeng, Jing, Roscoe, Benjamin P., Liu, Pengpeng, Yao, Qiuming, Lazzarotto, Cicera R., Clement, M. Kendell, Cole, Mitchel A., Luk, Kevin, Baricordi, Cristina, Shen, Anne H., Ren, Chunyan, Esrick, Erica B., Manis, John P., Dorfman, David M., Williams, David A., Biffi, Alessandra, Brugnara, Carlo, Biasco, Luca, Brendel, Christian, Pinello, Luca, Tsai, Shengdar Q., Wolfe, Scot A., Bauer, Daniel E.
Publicado no Nat Med (2019)

Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

Por Mavor, David, Barlow, Kyle, Thompson, Samuel, Barad, Benjamin A, Bonny, Alain R, Cario, Clinton L, Gaskins, Garrett, Liu, Zairan, Deming, Laura, Axen, Seth D, Caceres, Elena, Chen, Weilin, Cuesta, Adolfo, Gate, Rachel E, Green, Evan M, Hulce, Kaitlin R, Ji, Weiyue, Kenner, Lillian R, Mensa, Bruk, Morinishi, Leanna S, Moss, Steven M, Mravic, Marco, Muir, Ryan K, Niekamp, Stefan, Nnadi, Chimno I, Palovcak, Eugene, Poss, Erin M, Ross, Tyler D, Salcedo, Eugenia C, See, Stephanie K, Subramaniam, Meena, Wong, Allison W, Li, Jennifer, Thorn, Kurt S, Conchúir, Shane Ó, Roscoe, Benjamin P, Chow, Eric D, DeRisi, Joseph L, Kortemme, Tanja, Bolon, Daniel N, Fraser, James S
Publicado no eLife (2016)