ER stress sensing mechanism: Putting off the brake on UPR transducers

door Rojas-Rivera, Diego, Rodriguez, Diego A., Sepulveda, Denisse, Hetz, Claudio
Gepubliceerd in Oncotarget (2018)

When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157

door Rojas-Rivera, Diego, Delvaeye, Tinneke, Roelandt, Ria, Nerinckx, Wim, Augustyns, Koen, Vandenabeele, Peter, Bertrand, Mathieu J M
Gepubliceerd in Cell Death Differ (2017)

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

door Nassif, Melissa, Valenzuela, Vicente, Rojas-Rivera, Diego, Vidal, René, Matus, Soledad, Castillo, Karen, Fuentealba, Yerko, Kroemer, Guido, Levine, Beth, Hetz, Claudio
Gepubliceerd in 2014

A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway

door Zamorano, Sebastián, Rojas-Rivera, Diego, Lisbona, Fernanda, Parra, Valentina, Court, Felipe A., Villegas, Rosario, Cheng, Emily H., Korsmeyer, Stanley J., Lavandero, Sergio, Hetz, Claudio
Gepubliceerd in 2012

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

door Castillo, Karen, Rojas-Rivera, Diego, Lisbona, Fernanda, Caballero, Benjamín, Nassif, Melissa, Court, Felipe A, Schuck, Sebastian, Ibar, Consuelo, Walter, Peter, Sierralta, Jimena, Glavic, Alvaro, Hetz, Claudio
Gepubliceerd in 2011

BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

door Castillo, Karen, Rojas‐Rivera, Diego, Lisbona, Fernanda, Caballero, Benjamín, Nassif, Melissa, Court, Felipe A, Schuck, Sebastian, Ibar, Consuelo, Walter, Peter, Sierralta, Jimena, Glavic, Alvaro, Hetz, Claudio
Gepubliceerd in EMBO J (2017)

BAX Inhibitor-1 is a negative regulator of the ER stress sensor IRE1α

door Lisbona, Fernanda, Rojas-Rivera, Diego, Thielen, Peter, Zamorano, Sebastian, Todd, Derrick, Martinon, Fabio, Glavic, Alvaro, Kress, Christina, Lin, Jonathan H., Walter, Peter, Reed, John C., Glimcher, Laurie H., Hetz, Claudio
Gepubliceerd in 2009

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

door Dondelinger, Yves, Delanghe, Tom, Priem, Dario, Wynosky-Dolfi, Meghan A., Sorobetea, Daniel, Rojas-Rivera, Diego, Giansanti, Piero, Roelandt, Ria, Gropengiesser, Julia, Ruckdeschel, Klaus, Savvides, Savvas N., Heck, Albert J. R., Vandenabeele, Peter, Brodsky, Igor E., Bertrand, Mathieu J. M.
Gepubliceerd in Nat Commun (2019)

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α

door Rodriguez, Diego A, Zamorano, Sebastian, Lisbona, Fernanda, Rojas-Rivera, Diego, Urra, Hery, Cubillos-Ruiz, Juan R, Armisen, Ricardo, Henriquez, Daniel R, H Cheng, Emily, Letek, Michal, Vaisar, Tomas, Irrazabal, Thergiory, Gonzalez-Billault, Christian, Letai, Anthony, Pimentel-Muiños, Felipe X, Kroemer, Guido, Hetz, Claudio
Gepubliceerd in 2012

Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis

door Groenendyk, Jody, Peng, Zhenling, Dudek, Elzbieta, Fan, Xiao, Mizianty, Marcin J., Dufey, Estefanie, Urra, Hery, Sepulveda, Denisse, Rojas-Rivera, Diego, Lim, Yunki, Kim, Do Han, Baretta, Kayla, Srikanth, Sonal, Gwack, Yousang, Ahnn, Joohong, Kaufman, Randal J., Lee, Sun-Kyung, Hetz, Claudio, Kurgan, Lukasz, Michalak, Marek
Gepubliceerd in Sci Signal (2014)