iPSC-Based Drug Screening for Huntington’s Disease

Por Zhang, Ningzhe, Bailus, Barbara J., Ring, Karen L., Ellerby, Lisa M.
Publicado no Brain Res (2015)

Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

Por Naphade, Swati, Embusch, Alexander, Madushani, Kuruwitage Lakshika, Ring, Karen L., Ellerby, Lisa M.
Publicado no Front Neurosci (2018)

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Por Ring, Karen L., Tong, Leslie M., Balestra, Maureen E., Javier, Robyn, Andrews-Zwilling, Yaisa, Li, Gang, Walker, David, Zhang, William R., Kreitzer, Anatol C., Huang, Yadong
Publicado em 2012

Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells

Por Ring, Karen L., An, Mahru C., Zhang, Ningzhe, O’Brien, Robert N., Ramos, Eliana Marisa, Gao, Fuying, Atwood, Robert, Bailus, Barbara J., Melov, Simon, Mooney, Sean D., Coppola, Giovanni, Ellerby, Lisa M.
Publicado no Stem Cell Reports (2015)

Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo

Por O'Brien, Robert, DeGiacomo, Francesco, Holcomb, Jennifer, Bonner, Akilah, Ring, Karen L., Zhang, Ningzhe, Zafar, Khan, Weiss, Andreas, Lager, Brenda, Schilling, Birgit, Gibson, Bradford W., Chen, Sylvia, Kwak, Seung, Ellerby, Lisa M.
Publicado no J Biol Chem (2015)

Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells

Por Fong, Helen, Wang, Chengzhong, Knoferle, Johanna, Walker, David, Balestra, Maureen E., Tong, Leslie M., Leung, Laura, Ring, Karen L., Seeley, William W., Karydas, Anna, Kshirsagar, Mihir A., Boxer, Adam L., Kosik, Kenneth S., Miller, Bruce L., Huang, Yadong
Publicado em 2013