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iPSC-Based Drug Screening for Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder, caused by an expansion of the CAG repeat in exon 1 of the huntingtin gene. The disease generally manifests in middle age with both physical and mental symptoms. There are no effective treatments or cures and death usually...
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| Veröffentlicht in: | Brain Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814369/ https://ncbi.nlm.nih.gov/pubmed/26428226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.09.020 |
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