Rapid Pd-Catalyzed Synthesis of Piperazine Scaffolds Under Aerobic and Solvent-Free Conditions

Por Reilly, Sean W., Mach, Robert H.
Publicado no Org Lett (2016)

Rapid Cu-Catalyzed [(211)At]Astatination and [(125)I]Iodination of Boronic Esters at Room Temperature

Por Reilly, Sean W., Makvandi, Mehran, Xu, Kuiying, Mach, Robert H.
Publicado no Org Lett (2018)

Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase-1 Inhibitors with Decreased P-Glycoprotein Interactions

Por Reilly, Sean W., Puentes, Laura N., Hsieh, Chia-Ju, Makvandi, Mehran, Mach, Robert H.
Publicado no ACS Omega (2018)

Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity

Por Reilly, Sean W., Puentes, Laura N., Wilson, Khadija, Hsieh, Chia-Ju, Weng, Chi-Chang, Makvandi, Mehran, Mach, Robert H.
Publicado no J Med Chem (2018)

Highly Selective Dopamine D(3) Receptor Antagonists with Arylated Diazaspiro Alkane Cores

Por Reilly, Sean W., Griffin, Suzy, Taylor, Michelle, Sahlholm, Kristoffer, Weng, Chi-Chang, Xu, Kuiying, Jacome, Daniel A., Luedtke, Robert R., Mach, Robert H.
Publicado no J Med Chem (2017)

Synthesis and Evaluation of an AZD2461 [(18)F]PET Probe in Non-Human Primates Reveals the PARP-1 Inhibitor to be Non-Blood-Brain Barrier Penetrant

Por Reilly, Sean W., Puentes, Laura N., Schmitz, Alexander, Hsieh, Chia-Ju, Weng, Chi-Chang, Hou, Catherine, Li, Shihong, Kuo, Yin-Ming, Padakanti, Prashanth, Lee, Hsiaoju, Riad, Aladdin A., Makvandi, Mehran, Mach, Robert H.
Publicado no Bioorg Chem (2018)

Targeting PARP-1 with alpha-particles is potently cytotoxic to human neuroblastoma in pre-clinical models

Por Makvandi, Mehran, Lee, Hwan, Puentes, Laura N., Reilly, Sean W., Rathi, Komal S., Weng, Chi-Chang, Chan, Ho Sze, Hou, Catherine, Raman, Pichai, Martinez, Daniel, Xu, Kuiying, Carlin, Sean D., Greenberg, Roger A., Pawel, Bruce R., Mach, Robert H., Maris, John M., Pryma, Daniel A.
Publicado no Mol Cancer Ther (2019)