Small molecules, both dietary and endogenous, influence the onset of lens cataracts

Por Barnes, Stephen, Quinlan, Roy A.
Publicado no Exp Eye Res (2016)

Chaperones: needed for both the good times and the bad times

Por Quinlan, Roy A., Ellis, R. John
Publicado em 2013

Truncation of αB-Crystallin by the Myopathy-causing Q151X Mutation Significantly Destabilizes the Protein Leading to Aggregate Formation in Transfected Cells

Por Hayes, Victoria H., Devlin, Glyn, Quinlan, Roy A.
Publicado em 2008

Insights into the beaded filament of the eye lens

Por Perng, Ming-Der, Zhang, Qingjiong, Quinlan, Roy A.
Publicado no Exp Cell Res (2007)

GFAP and its role in Alexander Disease

Por Quinlan, Roy A, Brenner, Michael, Goldman, James E., Messing, Albee
Publicado em 2007

Multiple Sites in αB-Crystallin Modulate Its Interactions with Desmin Filaments Assembled In Vitro

Por Houck, Scott A., Landsbury, Andrew, Clark, John I., Quinlan, Roy A.
Publicado em 2011

The functional roles of the unstructured N- and C-terminal regions in αB-crystallin and other mammalian small heat-shock proteins

Por Carver, John A., Grosas, Aidan B., Ecroyd, Heath, Quinlan, Roy A.
Publicado no Cell Stress Chaperones (2017)

Lamin A/C Binding Protein LAP2α Is Required for Nuclear Anchorage of Retinoblastoma Protein

Por Markiewicz, Ewa, Dechat, Thomas, Foisner, Roland, Quinlan, Roy. A, Hutchison, Christopher J.
Publicado em 2002

A cell polarity protein aPKCλ is required for eye lens formation and growth

Por Sugiyama, Yuki, Akimoto, Kazunori, Robinson, Michael L., Ohno, Shigeo, Quinlan, Roy A.
Publicado em 2009

Radiation protection of the eye lens in medical workers—basis and impact of the ICRP recommendations

Por Barnard, Stephen GR, Ainsbury, Elizabeth A, Quinlan, Roy A, Bouffler, Simon D
Publicado no Br J Radiol (2016)

Antagonistic action of Six3 and Prox1 at the γ-crystallin promoter

Por Lengler, Johannes, Krausz, Eberhard, Tomarev, Stanislav, Prescott, Alan, Quinlan, Roy A., Graw, Jochen
Publicado em 2001

Functions of the intermediate filament cytoskeleton in the eye lens

Por Song, Shuhua, Landsbury, Andrew, Dahm, Ralf, Liu, Yizhi, Zhang, Qingjiong, Quinlan, Roy A.
Publicado em 2009

Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the α-crystallin domain

Por Quinlan, Roy A., Zhang, Yan, Lansbury, Andrew, Williamson, Ian, Pohl, Ehmke, Sun, Fei
Publicado em 2013

Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation

Por Chen, Mei-Hsuan, Hagemann, Tracy L., Quinlan, Roy A., Messing, Albee, Perng, Ming-Der
Publicado em 2013

A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells()

Por Wu, Weiju, Tholozan, Frederique M., Goldberg, Martin W., Bowen, Leon, Wu, Junjie, Quinlan, Roy A.
Publicado em 2014

Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrea...

Por Chen, Yi-Song, Lim, Suh-Ciuan, Chen, Mei-Hsuan, Quinlan, Roy A., Perng, Ming-Der
Publicado no Exp Cell Res (2011)

Desmin Aggregate Formation by R120G αB-Crystallin Is Caused by Altered Filament Interactions and Is Dependent upon Network Status in Cells

Por Der Perng, Ming, Wen, Shu Fang, van den IJssel, Paul, Prescott, Alan R., Quinlan, Roy A.
Publicado em 2004

Homeostasis in the vertebrate lens: mechanisms of solute exchange

Por Dahm, Ralf, van Marle, Jan, Quinlan, Roy A., Prescott, Alan R., Vrensen, Gijs F. J. M.
Publicado em 2011

αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Por Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Publicado no Cell Stress Chaperones (2017)

A dimensionless ordered pull-through model of the mammalian lens epithelium evidences scaling across species and explains the age-dependent changes in cell density in the human len...

Por Wu, Jun Jie, Wu, Weiju, Tholozan, Frederique M., Saunter, Christopher D., Girkin, John M., Quinlan, Roy A.
Publicado no J R Soc Interface (2015)