The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions

di Abdulrahman, Basant A., Abdelaziz, Dalia, Thapa, Simrika, Lu, Li, Jain, Shubha, Gilch, Sabine, Proniuk, Stefan, Zukiwski, Alexander, Schatzl, Hermann M.
Pubblicato in Sci Rep (2017)

AR-12 Inhibits Chaperone Proteins Preventing Virus Replication and the Accumulation of Toxic Misfolded Proteins

di Booth, Laurence, Roberts, Jane L, Ecroyd, Heath, Reid, St. Patrick, Proniuk, Stefan, Zukiwski, Alexander, Jacob, Abraham, Damonte, Elsa, Tuñón, María J, Dent, Paul
Pubblicato in J Clin Cell Immunol (2016)

ACTR-40. PHASE 2 SAFETY AND EFFICACY OF AR-67 (7-T-BUTYLDIMETHYLSILTYL-10-HYDROXYCAMPTOTHECIN) IN PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME (GBM) OR GLIOSARCOMA

di Kumthekar, Priya, Raizer, Jeffrey, Cavaliere, Robert, Devoe, Craig, Jensen, Randy, Stieber, Volker, Runk, Tina, Grewal, Jai, Brownell, Elise, Zukiwski, Alex, Proniuk, Stefan, Arnold, Susanne, Vredenburgh, James
Pubblicato in Neuro Oncol (2019)

Multi-kinase inhibitors can associate with heat shock proteins through their NH(2)-termini by which they suppress chaperone function

di Booth, Laurence, Shuch, Brian, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Proniuk, Stefan, Zukiwski, Alexander, Wang, Dasheng, Chen, Ching-Shih, Bottaro, Don, Ecroyd, Heath, Lebedyeva, Iryna O., Dent, Paul
Pubblicato in Oncotarget (2016)

AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication

di BOOTH, LAURENCE, ROBERTS, JANE L., ECROYD, HEATH, TRITSCH, SARAH R., BAVARI, SINA, REID, ST. PATRICK, PRONIUK, STEFAN, ZUKIWSKI, ALEXANDER, JACOB, ABRAHAM, SEPÚLVEDA, CLAUDIA S., GIOVANNONI, FEDERICO, GARCÍA, CYBELE C., DAMONTE, ELSA, GONZÁLEZ-GALLEGO, JAVIER, TUÑÓN, MARÍA J., DENT, PAUL
Pubblicato in J Cell Physiol (2016)

Phase I study of onapristone, a type I antiprogestin, in female patients with previously treated recurrent or metastatic progesterone receptor-expressing cancers

di Cottu, Paul H., Bonneterre, Jacques, Varga, Andrea, Campone, Mario, Leary, Alexandra, Floquet, Anne, Berton-Rigaud, Dominique, Sablin, Marie-Paule, Lesoin, Anne, Rezai, Keyvan, Lokiec, François M., Lhomme, Catherine, Bosq, Jacques, Bexon, Alice S., Gilles, Erard M., Proniuk, Stefan, Dieras, Veronique, Jackson, David M., Zukiwski, Alexander, Italiano, Antoine
Pubblicato in PLoS One (2018)