Kinetic Profile and Molecular Dynamic Studies Show that Y229W Substitution in an NDM-1/L209F Variant Restores the Hydrolytic Activity of the Enzyme toward Penicillins, Cephalospori...

Por Piccirilli, Alessandra, Brisdelli, Fabrizia, Aschi, Massimiliano, Celenza, Giuseppe, Amicosante, Gianfranco, Perilli, Mariagrazia
Publicado no Antimicrob Agents Chemother (2019)

P174E Substitution in GES-1 and GES-5 β-Lactamases Improves Catalytic Efficiency toward Carbapenems

Por Piccirilli, Alessandra, Mercuri, Paola Sandra, Galleni, Moreno, Aschi, Massimiliano, Matagne, André, Amicosante, Gianfranco, Perilli, Mariagrazia
Publicado no Antimicrob Agents Chemother (2018)

TEM-184, a Novel TEM-Derived Extended-Spectrum β-Lactamase with Enhanced Activity against Aztreonam

Por Piccirilli, Alessandra, Perilli, Mariagrazia, Amicosante, Gianfranco, Conte, Viola, Tascini, Carlo, Rossolini, Gian Maria, Giani, Tommaso
Publicado no Antimicrob Agents Chemother (2018)

Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems

Por Bottoni, Carlo, Perilli, Mariagrazia, Marcoccia, Francesca, Piccirilli, Alessandra, Pellegrini, Cristina, Colapietro, Martina, Sabatini, Alessia, Celenza, Giuseppe, Kerff, Frédéric, Amicosante, Gianfranco, Galleni, Moreno, Mercuri, Paola Sandra
Publicado no Antimicrob Agents Chemother (2016)