731. Pharmacokinetics of Gepotidacin (GSK2140944) in Subjects with Hepatic Impairment

Yazar: Hands, Jonathan T, Tao, Yu, Tiffany, Courtney, Perry, Caroline R, Dumont, Etienne, Hossain, Mohammad
Yayımlandı Open Forum Infect Dis (2019)

Sources and Importance of Mitochondrial NAD

Yazar: Baur, Joseph, Luongo, Timothy, Eller, Jared, Lu, Mu-Jie, Perry, Caroline, Cambronne, Lulu
Yayımlandı Innov Aging (2020)

Albiglutide Does Not Prolong QTc Interval in Healthy Subjects: A Thorough ECG Study

Yazar: Darpo, Borje, Zhou, Meijian, Matthews, Jessica, Zhi, Hui, Young, Malcolm A., Perry, Caroline, Reinhardt, Rickey R.
Baskı/Yayın Bilgisi 2014

Erratum to: Albiglutide Does Not Prolong QTc Interval in Healthy Subjects: A Thorough ECG Study

Yazar: Darpo, Borje, Zhou, Meijian, Matthews, Jessica, Zhi, Hui, Young, Malcolm A., Perry, Caroline, Reinhardt, Rickey R.
Yayımlandı Diabetes Ther (2014)

Efficacy, Safety, and Tolerability of Gepotidacin (GSK2140944) in the Treatment of Patients with Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infect...

Yazar: O'Riordan, William, Tiffany, Courtney, Scangarella-Oman, Nicole, Perry, Caroline, Hossain, Mohammad, Ashton, Teri, Dumont, Etienne
Yayımlandı Antimicrob Agents Chemother (2017)

1482. Microbiological Analysis from a Phase II Study Evaluating Gepotidacin (GSK2140944) in the Treatment of Uncomplicated Urinary Tract Infections

Yazar: Scangarella-Oman, Nicole, Hossain, Mohammad, Tiemeyer Jr., Timothy, Perry, Caroline R, Tiffany, Courtney, Raychaudhuri, Aparna, Dumont, Etienne
Yayımlandı Open Forum Infect Dis (2019)

1480. Plasma and Urine Pharmacokinetic Analysis of Gepotidacin (GSK2140944) Following BID Oral Dosing in a Phase IIa Study for Treatment of Uncomplicated Urinary Tract Infections

Yazar: Zimmerman, Eric I, Dumont, Etienne, Perry, Caroline R, Tiffany, Courtney, Scangarella-Oman, Nicole, Raychaudhuri, Aparna, Hossain, Mohammad
Yayımlandı Open Forum Infect Dis (2019)

1479. Clinical Efficacy and Safety Analysis Evaluating Oral Gepotidacin (GSK2140944) from a Phase IIa Study in the Treatment of Uncomplicated Urinary Tract Infections

Yazar: Overcash, J Scott, Dumont, Etienne, Perry, Caroline R, Tiffany, Courtney, Scangarella-Oman, Nicole, Raychaudhuri, Aparna, Hossain, Mohammad
Yayımlandı Open Forum Infect Dis (2019)

Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with typ...

Yazar: Nauck, Michael A., Stewart, Murray W., Perkins, Christopher, Jones-Leone, Angela, Yang, Fred, Perry, Caroline, Reinhardt, Rickey R., Rendell, Marc
Yayımlandı Diabetologia (2015)

1281. Longitudinal and Spatial Variation in the Human Microbiome in a Phase 2a Clinical Study of Gepotidacin in Adult Females with Uncomplicated Urinary Tract Infection

Yazar: Nuzzo, Andrea, Van Horn, Stephanie, Traini, Christopher, Perry, Caroline R, Dumont, Etienne, Scangarella-Oman, Nicole, Gardiner, David, Brown, James R
Yayımlandı Open Forum Infect Dis (2020)

Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants with Uncomplicated Urinary Tract Infection (Acute Unco...

Yazar: Overcash, J. Scott, Tiffany, Courtney A., Scangarella-Oman, Nicole E., Perry, Caroline R., Tao, Yu, Hossain, Mohammad, Barth, Aline, Dumont, Etienne F.
Yayımlandı Antimicrob Agents Chemother (2020)

Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK140944)

Yazar: Nuzzo, Andrea, Van Horn, Stephanie, Traini, Christopher, Perry, Caroline R., Dumont, Etienne F., Scangarella-Oman, Nicole E., Gardiner, David F., Brown, James R.
Yayımlandı BMC Microbiol (2021)

Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds

Yazar: Childers, Gabrielle M., Perry, Caroline A., Blachut, Barbara, Martin, Negin, Bortner, Carl D., Sieber, Stella, Li, Jian-Liang, Fessler, Michael B., Harry, G. Jean
Yayımlandı Environ Health Perspect (2021)

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

Yazar: Mukherjee, Sarmistha, Mo, James, Paolella, Lauren M., Perry, Caroline E., Toth, Jade, Hugo, Mindy M., Chu, Qingwei, Tong, Qiang, Chellappa, Karthikeyani, Baur, Joseph A.
Yayımlandı JCI Insight (2021)

Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection

Yazar: Beier, Ulf H., Hartung, Erum A., Concors, Seth, Hernandez, Paul T., Wang, Zhonglin, Perry, Caroline, Baur, Joseph A., Denburg, Michelle R., Hancock, Wayne W., Gade, Terence P., Levine, Matthew H.
Yayımlandı Metabolomics (2020)

Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation

Yazar: Taylor, Stephanie N, Morris, David H, Avery, Ann K, Workowski, Kimberly A, Batteiger, Byron E, Tiffany, Courtney A, Perry, Caroline R, Raychaudhuri, Aparna, Scangarella-Oman, Nicole E, Hossain, Mohammad, Dumont, Etienne F
Yayımlandı Clin Infect Dis (2018)

Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neis...

Yazar: Scangarella-Oman, Nicole E., Hossain, Mohammad, Dixon, Paula B., Ingraham, Karen, Min, Sharon, Tiffany, Courtney A., Perry, Caroline R., Raychaudhuri, Aparna, Dumont, Etienne F., Huang, Jianzhong, Hook, Edward W., Miller, Linda A.
Yayımlandı Antimicrob Agents Chemother (2018)

In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure I...

Yazar: Scangarella-Oman, Nicole E., Ingraham, Karen A., Tiffany, Courtney A., Tomsho, Lynn, Van Horn, Stephanie F., Mayhew, David N., Perry, Caroline R., Ashton, Theresa C., Dumont, Etienne F., Huang, Jianzhong, Brown, James R., Miller, Linda A.
Yayımlandı Antimicrob Agents Chemother (2020)

Polyunsaturated Fatty Acids from Astrocytes Activate PPAR Gamma Signaling in Cancer Cells to Promote Brain Metastasis

Yazar: Zou, Yongkang, Watters, Andrea, Cheng, Nan, Perry, Caroline E, Xu, Ke, Alicea, Gretchen M, Parris, Joshua L.D, Baraban, Ezra, Ray, Pulak, Nayak, Anupma, Xu, Xiaowei, Herlyn, Meenhard, Murphy, Maureen E, Weeraratna, Ashani T, Schug, Zachary T., Chen, Qing
Yayımlandı Cancer Discov (2019)

Using rapid point-of-care tests to inform antibiotic choice to mitigate drug resistance in gonorrhoea

Yazar: Vegvari, Carolin, Grad, Yonatan H, White, Peter J, Didelot, Xavier, Whittles, Lilith K, Scangarella-Oman, Nicole E, Mitrani-Gold, Fanny S, Dumont, Etienne, Perry, Caroline R, Gilchrist, Kim, Hossain, Mohammad, Mortimer, Tatum D, Anderson, Roy M, Gardiner, David
Yayımlandı Euro Surveill (2020)