731. Pharmacokinetics of Gepotidacin (GSK2140944) in Subjects with Hepatic Impairment

по Hands, Jonathan T, Tao, Yu, Tiffany, Courtney, Perry, Caroline R, Dumont, Etienne, Hossain, Mohammad
Опубликовано в: Open Forum Infect Dis (2019)

Sources and Importance of Mitochondrial NAD

по Baur, Joseph, Luongo, Timothy, Eller, Jared, Lu, Mu-Jie, Perry, Caroline, Cambronne, Lulu
Опубликовано в: Innov Aging (2020)

Albiglutide Does Not Prolong QTc Interval in Healthy Subjects: A Thorough ECG Study

по Darpo, Borje, Zhou, Meijian, Matthews, Jessica, Zhi, Hui, Young, Malcolm A., Perry, Caroline, Reinhardt, Rickey R.
Опубликовано 2014

Erratum to: Albiglutide Does Not Prolong QTc Interval in Healthy Subjects: A Thorough ECG Study

по Darpo, Borje, Zhou, Meijian, Matthews, Jessica, Zhi, Hui, Young, Malcolm A., Perry, Caroline, Reinhardt, Rickey R.
Опубликовано в: Diabetes Ther (2014)

Efficacy, Safety, and Tolerability of Gepotidacin (GSK2140944) in the Treatment of Patients with Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infect...

по O'Riordan, William, Tiffany, Courtney, Scangarella-Oman, Nicole, Perry, Caroline, Hossain, Mohammad, Ashton, Teri, Dumont, Etienne
Опубликовано в: Antimicrob Agents Chemother (2017)

1482. Microbiological Analysis from a Phase II Study Evaluating Gepotidacin (GSK2140944) in the Treatment of Uncomplicated Urinary Tract Infections

по Scangarella-Oman, Nicole, Hossain, Mohammad, Tiemeyer Jr., Timothy, Perry, Caroline R, Tiffany, Courtney, Raychaudhuri, Aparna, Dumont, Etienne
Опубликовано в: Open Forum Infect Dis (2019)

1480. Plasma and Urine Pharmacokinetic Analysis of Gepotidacin (GSK2140944) Following BID Oral Dosing in a Phase IIa Study for Treatment of Uncomplicated Urinary Tract Infections

по Zimmerman, Eric I, Dumont, Etienne, Perry, Caroline R, Tiffany, Courtney, Scangarella-Oman, Nicole, Raychaudhuri, Aparna, Hossain, Mohammad
Опубликовано в: Open Forum Infect Dis (2019)

1479. Clinical Efficacy and Safety Analysis Evaluating Oral Gepotidacin (GSK2140944) from a Phase IIa Study in the Treatment of Uncomplicated Urinary Tract Infections

по Overcash, J Scott, Dumont, Etienne, Perry, Caroline R, Tiffany, Courtney, Scangarella-Oman, Nicole, Raychaudhuri, Aparna, Hossain, Mohammad
Опубликовано в: Open Forum Infect Dis (2019)

Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with typ...

по Nauck, Michael A., Stewart, Murray W., Perkins, Christopher, Jones-Leone, Angela, Yang, Fred, Perry, Caroline, Reinhardt, Rickey R., Rendell, Marc
Опубликовано в: Diabetologia (2015)

1281. Longitudinal and Spatial Variation in the Human Microbiome in a Phase 2a Clinical Study of Gepotidacin in Adult Females with Uncomplicated Urinary Tract Infection

по Nuzzo, Andrea, Van Horn, Stephanie, Traini, Christopher, Perry, Caroline R, Dumont, Etienne, Scangarella-Oman, Nicole, Gardiner, David, Brown, James R
Опубликовано в: Open Forum Infect Dis (2020)

Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants with Uncomplicated Urinary Tract Infection (Acute Unco...

по Overcash, J. Scott, Tiffany, Courtney A., Scangarella-Oman, Nicole E., Perry, Caroline R., Tao, Yu, Hossain, Mohammad, Barth, Aline, Dumont, Etienne F.
Опубликовано в: Antimicrob Agents Chemother (2020)

Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK140944)

по Nuzzo, Andrea, Van Horn, Stephanie, Traini, Christopher, Perry, Caroline R., Dumont, Etienne F., Scangarella-Oman, Nicole E., Gardiner, David F., Brown, James R.
Опубликовано в: BMC Microbiol (2021)

Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds

по Childers, Gabrielle M., Perry, Caroline A., Blachut, Barbara, Martin, Negin, Bortner, Carl D., Sieber, Stella, Li, Jian-Liang, Fessler, Michael B., Harry, G. Jean
Опубликовано в: Environ Health Perspect (2021)

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

по Mukherjee, Sarmistha, Mo, James, Paolella, Lauren M., Perry, Caroline E., Toth, Jade, Hugo, Mindy M., Chu, Qingwei, Tong, Qiang, Chellappa, Karthikeyani, Baur, Joseph A.
Опубликовано в: JCI Insight (2021)

Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection

по Beier, Ulf H., Hartung, Erum A., Concors, Seth, Hernandez, Paul T., Wang, Zhonglin, Perry, Caroline, Baur, Joseph A., Denburg, Michelle R., Hancock, Wayne W., Gade, Terence P., Levine, Matthew H.
Опубликовано в: Metabolomics (2020)

Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation

по Taylor, Stephanie N, Morris, David H, Avery, Ann K, Workowski, Kimberly A, Batteiger, Byron E, Tiffany, Courtney A, Perry, Caroline R, Raychaudhuri, Aparna, Scangarella-Oman, Nicole E, Hossain, Mohammad, Dumont, Etienne F
Опубликовано в: Clin Infect Dis (2018)

Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neis...

по Scangarella-Oman, Nicole E., Hossain, Mohammad, Dixon, Paula B., Ingraham, Karen, Min, Sharon, Tiffany, Courtney A., Perry, Caroline R., Raychaudhuri, Aparna, Dumont, Etienne F., Huang, Jianzhong, Hook, Edward W., Miller, Linda A.
Опубликовано в: Antimicrob Agents Chemother (2018)

In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure I...

по Scangarella-Oman, Nicole E., Ingraham, Karen A., Tiffany, Courtney A., Tomsho, Lynn, Van Horn, Stephanie F., Mayhew, David N., Perry, Caroline R., Ashton, Theresa C., Dumont, Etienne F., Huang, Jianzhong, Brown, James R., Miller, Linda A.
Опубликовано в: Antimicrob Agents Chemother (2020)

Polyunsaturated Fatty Acids from Astrocytes Activate PPAR Gamma Signaling in Cancer Cells to Promote Brain Metastasis

по Zou, Yongkang, Watters, Andrea, Cheng, Nan, Perry, Caroline E, Xu, Ke, Alicea, Gretchen M, Parris, Joshua L.D, Baraban, Ezra, Ray, Pulak, Nayak, Anupma, Xu, Xiaowei, Herlyn, Meenhard, Murphy, Maureen E, Weeraratna, Ashani T, Schug, Zachary T., Chen, Qing
Опубликовано в: Cancer Discov (2019)

Using rapid point-of-care tests to inform antibiotic choice to mitigate drug resistance in gonorrhoea

по Vegvari, Carolin, Grad, Yonatan H, White, Peter J, Didelot, Xavier, Whittles, Lilith K, Scangarella-Oman, Nicole E, Mitrani-Gold, Fanny S, Dumont, Etienne, Perry, Caroline R, Gilchrist, Kim, Hossain, Mohammad, Mortimer, Tatum D, Anderson, Roy M, Gardiner, David
Опубликовано в: Euro Surveill (2020)