Could the Inhibition of Endo-Lysosomal Two-Pore Channels (TPCs) by the Natural Flavonoid Naringenin Represent an Option to Fight SARS-CoV-2 Infection?

מאת Filippini, Antonio, D'Amore, Antonella, Palombi, Fioretta, Carpaneto, Armando
הוצא לאור ב Front Microbiol (2020)

Ned-19 inhibition of parasite growth and multiplication suggests a role for NAADP mediated signalling in the asexual development of Plasmodium falciparum

מאת Suárez-Cortés, Pablo, Gambara, Guido, Favia, Annarita, Palombi, Fioretta, Alano, Pietro, Filippini, Antonio
הוצא לאור ב Malar J (2017)

Regulation of Angiogenic Functions by Angiopoietins through Calcium-Dependent Signaling Pathways

מאת Pafumi, Irene, Favia, Annarita, Gambara, Guido, Papacci, Francesca, Ziparo, Elio, Palombi, Fioretta, Filippini, Antonio
הוצא לאור ב Biomed Res Int (2015)

The Discovery of Naringenin as Endolysosomal Two-Pore Channel Inhibitor and Its Emerging Role in SARS-CoV-2 Infection

מאת D’Amore, Antonella, Gradogna, Antonella, Palombi, Fioretta, Minicozzi, Velia, Ceccarelli, Matteo, Carpaneto, Armando, Filippini, Antonio
הוצא לאור ב Cells (2021)

Cyclic Expression of Endothelin-converting Enzyme-1 Mediates the Functional Regulation of Seminiferous Tubule Contraction

מאת Tripiciano, Antonella, Peluso, Carmelina, Morena, Anna Rita, Palombi, Fioretta, Stefanini, Mario, Ziparo, Elio, Yanagisawa, Masashi, Filippini, Antonio
יצא לאור 1999

Visual evoked potentials of Niemann-Pick type C1 mice reveal an impairment of the visual pathway that is rescued by 2-hydroxypropyl-ß-cyclodextrin

מאת Palladino, Giampiero, Loizzo, Stefano, Fortuna, Andrea, Canterini, Sonia, Palombi, Fioretta, Erickson, Robert P., Mangia, Franco, Fiorenza, Maria Teresa
הוצא לאור ב Orphanet J Rare Dis (2015)

Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis

מאת Paronetto, Maria Paola, Messina, Valeria, Bianchi, Enrica, Barchi, Marco, Vogel, Gillian, Moretti, Costanzo, Palombi, Fioretta, Stefanini, Mario, Geremia, Raffaele, Richard, Stéphane, Sette, Claudio
יצא לאור 2009

Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis

מאת Pafumi, Irene, Festa, Margherita, Papacci, Francesca, Lagostena, Laura, Giunta, Cristina, Gutla, Vijay, Cornara, Laura, Favia, Annarita, Palombi, Fioretta, Gambale, Franco, Filippini, Antonio, Carpaneto, Armando
הוצא לאור ב Sci Rep (2017)

Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entr...

מאת D’Amore, Antonella, Hanbashi, Ali Ahmed, Di Agostino, Silvia, Palombi, Fioretta, Sacconi, Andrea, Voruganti, Aniruddha, Taggi, Marilena, Canipari, Rita, Blandino, Giovanni, Parrington, John, Filippini, Antonio
הוצא לאור ב Cancers (Basel) (2020)

Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro

מאת Clementi, Nicola, Scagnolari, Carolina, D’Amore, Antonella, Palombi, Fioretta, Criscuolo, Elena, Frasca, Federica, Pierangeli, Alessandra, Mancini, Nicasio, Antonelli, Guido, Clementi, Massimo, Carpaneto, Armando, Filippini, Antonio
הוצא לאור ב Pharmacol Res (2021)

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2–dependent Ca(2+) signaling

מאת Favia, Annarita, Desideri, Marianna, Gambara, Guido, D’Alessio, Alessio, Ruas, Margarida, Esposito, Bianca, Del Bufalo, Donatella, Parrington, John, Ziparo, Elio, Palombi, Fioretta, Galione, Antony, Filippini, Antonio
הוצא לאור ב Proc Natl Acad Sci U S A (2014)

NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis

מאת Favia, Annarita, Pafumi, Irene, Desideri, Marianna, Padula, Fabrizio, Montesano, Camilla, Passeri, Daniela, Nicoletti, Carmine, Orlandi, Augusto, Del Bufalo, Donatella, Sergi, Manuel, Ziparo, Elio, Palombi, Fioretta, Filippini, Antonio
הוצא לאור ב Sci Rep (2016)

The Adherent/Invasive Escherichia coli Strain LF82 Invades and Persists in Human Prostate Cell Line RWPE-1, Activating a Strong Inflammatory Response

מאת Conte, Maria P., Aleandri, Marta, Marazzato, Massimiliano, Conte, Antonietta L., Ambrosi, Cecilia, Nicoletti, Mauro, Zagaglia, Carlo, Gambara, Guido, Palombi, Fioretta, De Cesaris, Paola, Ziparo, Elio, Palamara, Anna T., Riccioli, Anna, Longhi, Catia
הוצא לאור ב Infect Immun (2016)