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VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2–dependent Ca(2+) signaling
Vascular endothelial growth factor (VEGF) and its receptors VEGFR1/VEGFR2 play major roles in controlling angiogenesis, including vascularization of solid tumors. Here we describe a specific Ca(2+) signaling pathway linked to the VEGFR2 receptor subtype, controlling the critical angiogenic responses...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226099/ https://ncbi.nlm.nih.gov/pubmed/25331892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406029111 |
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