The Discovery of Naringenin as Endolysosomal Two-Pore Channel Inhibitor and Its Emerging Role in SARS-CoV-2 Infection

The flavonoid naringenin (Nar), present in citrus fruits and tomatoes, has been identified as a blocker of an emerging class of human intracellular channels, namely the two-pore channel (TPC) family, whose role has been established in several diseases. Indeed, Nar was shown to be effective against n...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: D’Amore, Antonella, Gradogna, Antonella, Palombi, Fioretta, Minicozzi, Velia, Ceccarelli, Matteo, Carpaneto, Armando, Filippini, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150892/
https://ncbi.nlm.nih.gov/pubmed/34067054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051130
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