Camelid V(H)H affinity ligands enable separation of closely related biopharmaceuticals

by Pabst, Timothy M., Wendeler, Michaela, Wang, Xiangyang, Bezemer, Sandra, Hermans, Pim, Hunter, Alan K.
Published in Biotechnol J (2016)

Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule elec...

by Du, Qun, Damschroder, Melissa, Pabst, Timothy M., Hunter, Alan K., Wang, William K., Luo, Haibin
Published in MAbs (2019)

Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

by Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.
Published in Biotechnol Prog (2018)

Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

by Linke, Thomas, Aspelund, Matthew T, Thompson, Christopher, Xi, Guoling, Fulton, Andrew, Wendeler, Michaela, Pabst, Timothy M, Wang, Xiangyang, Wang, William K, Ram, Kripa, Hunter, Alan K
Published in Biotechnol Prog (2014)