Camelid V(H)H affinity ligands enable separation of closely related biopharmaceuticals

von Pabst, Timothy M., Wendeler, Michaela, Wang, Xiangyang, Bezemer, Sandra, Hermans, Pim, Hunter, Alan K.
Veröffentlicht in Biotechnol J (2016)

Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule elec...

von Du, Qun, Damschroder, Melissa, Pabst, Timothy M., Hunter, Alan K., Wang, William K., Luo, Haibin
Veröffentlicht in MAbs (2019)

Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

von Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.
Veröffentlicht in Biotechnol Prog (2018)

Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

von Linke, Thomas, Aspelund, Matthew T, Thompson, Christopher, Xi, Guoling, Fulton, Andrew, Wendeler, Michaela, Pabst, Timothy M, Wang, Xiangyang, Wang, William K, Ram, Kripa, Hunter, Alan K
Veröffentlicht in Biotechnol Prog (2014)