Diaphragm adaptations in patients with COPD

Por Ottenheijm, Coen AC, Heunks, Leo MA, Dekhuijzen, Richard PN
Publicado em 2008

ALTERED CONTRACTILITY OF SKELETAL MUSCLE IN MICE DEFICIENT IN TITIN’S M-BAND REGION

Por Ottenheijm, Coen A.C., Hidalgo, Carlos, Rost, Katharina, Gotthardt, Michael, Granzier, Henk
Publicado em 2009

Differential splicing of the large sarcomeric protein nebulin during skeletal muscle development

Por Buck, Danielle, Hudson, Bryan D., Ottenheijm, Coen A.C., Labeit, Siegfried, Granzier, Henk
Publicado em 2010

Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy

Por Ottenheijm, Coen A.C., Lawlor, Michael W., Stienen, Ger J.M., Granzier, Henk, Beggs, Alan H.
Publicado em 2011

Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency

Por Ottenheijm, Coen A.C., Witt, Christian C., Stienen, Ger J., Labeit, Siegfried, Beggs, Alan H., Granzier, Henk
Publicado em 2009

ALTERED MYOFILAMENT FUNCTION DEPRESSES FORCE GENERATION IN PATIENTS WITH NEBULIN-BASED NEMALINE MYOPATHY (NEM2)

Por Ottenheijm, Coen A.C., Hooijman, Pleuni, DeChene, Elizabeth T., Stienen, Ger J., Beggs, Alan H., Granzier, Henk
Publicado em 2009

Tuning Passive Mechanics through Differential Splicing of Titin during Skeletal Muscle Development

Por Ottenheijm, Coen A.C., Knottnerus, Anna M., Buck, Danielle, Luo, Xiuju, Greer, Kevin, Hoying, Adam, Labeit, Siegfried, Granzier, Henk
Publicado em 2009

Experimentally Increasing TITIN Compliance in a Novel Mouse Model Attenuates the Frank-Starling Mechanism but has a Beneficial Effect on Diastole

Por Methawasin, Mei, Hutchinson, Kirk R, Lee, Eun-Jeong, Smith, John E, Saripalli, Chandra, Hidalgo, Carlos G, Ottenheijm, Coen AC, Granzier, Henk
Publicado em 2014

Gene expression profile in the diaphragm following contractile inactivity during thoracic surgery

Por Welvaart, Willem N, Paul, Marinus A, Kuster, Diederik WD, van Wieringen, WesselN, Rustenburg, Francois, Stienen, Ger JM, Vonk-Noordegraaf, Anton, Ottenheijm, Coen AC
Publicado em 2011

Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene

Por de Winter, Josine M, Joureau, Barbara, Sequeira, Vasco, Clarke, Nigel F, van der Velden, Jolanda, Stienen, Ger JM, Granzier, Henk, Beggs, Alan H, Ottenheijm, Coen AC
Publicado no Skelet Muscle (2015)

Sarcomeric dysfunction contributes to muscle weakness in facioscapulohumeral muscular dystrophy

Por Lassche, Saskia, Stienen, Ger J.M., Irving, Tom C., van der Maarel, Silvère M., Voermans, Nicol C., Padberg, George W., Granzier, Henk, van Engelen, Baziel G.M., Ottenheijm, Coen A.C.
Publicado em 2013

Determining the role of sarcomeric proteins in facioscapulohumeral muscular dystrophy: a study protocol

Por Lassche, Saskia, Ottenheijm, Coen AC, Voermans, Nicol C, Westeneng, Henk-Jan, Janssen, Barbara H, van der Maarel, Silvère M, Hopman, Maria T, Padberg, George W, Stienen, Ger JM, van Engelen, Baziel GM
Publicado em 2013

Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension: Relative Contribution of Fibrosis and Myofibril Stiffness

Por Rain, Silvia, Andersen, Stine, Najafi, Aref, Gammelgaard Schultz, Jacob, da Silva Gonçalves Bós, Denielli, Handoko, M. Louis, Bogaard, Harm-Jan, Vonk-Noordegraaf, Anton, Andersen, Asger, van der Velden, Jolanda, Ottenheijm, Coen A.C., de Man, Frances S.
Publicado no Circ Heart Fail (2016)

Muscle weakness in TPM3-myopathy is due to reduced Ca(2+)-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres

Por Yuen, Michaela, Cooper, Sandra T., Marston, Steve B., Nowak, Kristen J., McNamara, Elyshia, Mokbel, Nancy, Ilkovski, Biljana, Ravenscroft, Gianina, Rendu, John, de Winter, Josine M., Klinge, Lars, Beggs, Alan H., North, Kathryn N., Ottenheijm, Coen A.C., Clarke, Nigel F.
Publicado no Hum Mol Genet (2015)

Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype

Por Malfatti, Edoardo, Lehtokari, Vilma-Lotta, Böhm, Johann, De Winter, Josine M, Schäffer, Ursula, Estournet, Brigitte, Quijano-Roy, Susana, Monges, Soledad, Lubieniecki, Fabiana, Bellance, Remi, Viou, Mai Thao, Madelaine, Angéline, Wu, Bin, Taratuto, Ana Lía, Eymard, Bruno, Pelin, Katarina, Fardeau, Michel, Ottenheijm, Coen AC, Wallgren-Pettersson, Carina, Laporte, Jocelyn, Romero, Norma B
Publicado no Acta Neuropathol Commun (2014)

Diaphragm Fiber Strength Is Reduced in Critically Ill Patients and Restored by a Troponin Activator

Por Hooijman, Pleuni E., Beishuizen, Albertus, de Waard, Monique C., de Man, Frances S., Vermeijden, J. W., Steenvoorde, Pascal, Bouwman, R. Arthur, Lommen, Wies, van Hees, Hieronymus W.H., Heunks, Leo M.A., Dickhoff, Chris, van der Peet, Donald L., Girbes, Armand R. J., Jasper, Jeff R., Malik, Fady I., Stienen, Ger J.M., Hartemink, Koen J., Paul, Marinus A., Ottenheijm, Coen A.C.
Publicado no Am J Respir Crit Care Med (2014)

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

Por Yuen, Michaela, Sandaradura, Sarah A., Dowling, James J., Kostyukova, Alla S., Moroz, Natalia, Quinlan, Kate G., Lehtokari, Vilma-Lotta, Ravenscroft, Gianina, Todd, Emily J., Ceyhan-Birsoy, Ozge, Gokhin, David S., Maluenda, Jérome, Lek, Monkol, Nolent, Flora, Pappas, Christopher T., Novak, Stefanie M., D’Amico, Adele, Malfatti, Edoardo, Thomas, Brett P., Gabriel, Stacey B., Gupta, Namrata, Daly, Mark J., Ilkovski, Biljana, Houweling, Peter J., Davidson, Ann E., Swanson, Lindsay C., Brownstein, Catherine A., Gupta, Vandana A., Medne, Livija, Shannon, Patrick, Martin, Nicole, Bick, David P., Flisberg, Anders, Holmberg, Eva, Van den Bergh, Peter, Lapunzina, Pablo, Waddell, Leigh B., Sloboda, Darcée D., Bertini, Enrico, Chitayat, David, Telfer, William R., Laquerrière, Annie, Gregorio, Carol C., Ottenheijm, Coen A.C., Bönnemann, Carsten G., Pelin, Katarina, Beggs, Alan H., Hayashi, Yukiko K., Romero, Norma B., Laing, Nigel G., Nishino, Ichizo, Wallgren-Pettersson, Carina, Melki, Judith, Fowler, Velia M., MacArthur, Daniel G., North, Kathryn N., Clarke, Nigel F.
Publicado no J Clin Invest (2014)

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

Por Yuen, Michaela, Sandaradura, Sarah A., Dowling, James J., Kostyukova, Alla S., Moroz, Natalia, Quinlan, Kate G., Lehtokari, Vilma-Lotta, Ravenscroft, Gianina, Todd, Emily J., Ceyhan-Birsoy, Ozge, Gokhin, David S., Maluenda, Jérome, Lek, Monkol, Nolent, Flora, Pappas, Christopher T., Novak, Stefanie M., D’Amico, Adele, Malfatti, Edoardo, Thomas, Brett P., Gabriel, Stacey B., Gupta, Namrata, Daly, Mark J., Ilkovski, Biljana, Houweling, Peter J., Davidson, Ann E., Swanson, Lindsay C., Brownstein, Catherine A., Gupta, Vandana A., Medne, Livija, Shannon, Patrick, Martin, Nicole, Bick, David P., Flisberg, Anders, Holmberg, Eva, Van den Bergh, Peter, Lapunzina, Pablo, Waddell, Leigh B., Sloboda, Darcée D., Bertini, Enrico, Chitayat, David, Telfer, William R., Laquerrière, Annie, Gregorio, Carol C., Ottenheijm, Coen A.C., Bönnemann, Carsten G., Pelin, Katarina, Beggs, Alan H., Hayashi, Yukiko K., Romero, Norma B., Laing, Nigel G., Nishino, Ichizo, Wallgren-Pettersson, Carina, Melki, Judith, Fowler, Velia M., MacArthur, Daniel G., North, Kathryn N., Clarke, Nigel F.
Publicado no J Clin Invest (2015)