Perturbed proteostasis in autism spectrum disorders

af Louros, Susana R., Osterweil, Emily K.
Udgivet i J Neurochem (2016)

Myosin 1E interacts with synaptojanin-1 and dynamin via its SH3 domain

af Krendel, Mira, Osterweil, Emily K., Mooseker, Mark S.
Udgivet 2007

Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model

af Muscas, Melania, Louros, Susana R., Osterweil, Emily K.
Udgivet i eNeuro (2019)

Activation of mGluR5 Induces Rapid and Long-Lasting Protein Kinase D Phosphorylation in Hippocampal Neurons

af Krueger, Dilja D., Osterweil, Emily K., Bear, Mark F.
Udgivet 2010

Mutations causing syndromic autism define an axis of synaptic pathophysiology

af Auerbach, Benjamin D., Osterweil, Emily K., Bear, Mark F.
Udgivet 2011

A Differential Effect of Lovastatin versus Simvastatin in Neurodevelopmental Disorders

af Muscas, Melania, Seo, Sang S., Louros, Susana R., Osterweil, Emily K.
Udgivet i eNeuro (2020)

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

af Osterweil, Emily K., Krueger, Dilja D., Reinhold, Kimberly, Bear, Mark F.
Udgivet 2010

Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex

af Sidorov, Michael S., Kaplan, Eitan S., Osterweil, Emily K., Lindemann, Lothar, Bear, Mark F.
Udgivet i Proc Natl Acad Sci U S A (2015)

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

af Krueger, Dilja D., Osterweil, Emily K., Chen, Stephanie P., Tye, Lynne D., Bear, Mark F.
Udgivet 2011

Extinction of an instrumental response: A cognitive behavioral assay in Fmr1 knockout mice

af Sidorov, Michael S., Krueger, Dilja D., Taylor, Madison, Gisin, Eugenia, Osterweil, Emily K., Bear, Mark F.
Udgivet 2014

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

af Lohith, Talakad G, Osterweil, Emily K, Fujita, Masahiro, Jenko, Kimberly J, Bear, Mark F, Innis, Robert B
Udgivet 2013

Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome

af Tao, Jifang, Wu, Hao, Coronado, Amanda A., de Laittre, Elizabeth, Osterweil, Emily K., Zhang, Yi, Bear, Mark F.
Udgivet i J Neurosci (2016)

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

af Osterweil, Emily K., Chuang, Shih-Chieh, Chubykin, Alexander A., Sidorov, Michael, Bianchi, Riccardo, Wong, Robert K. S., Bear, Mark F.
Udgivet 2013

Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome

af Thomson, Sophie R., Seo, Sang S., Barnes, Stephanie A., Louros, Susana R., Muscas, Melania, Dando, Owen, Kirby, Caoimhe, Wyllie, David J.A., Hardingham, Giles E., Kind, Peter C., Osterweil, Emily K.
Udgivet i Neuron (2017)

Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS

af Till, Sally M., Asiminas, Antonis, Jackson, Adam D., Katsanevaki, Danai, Barnes, Stephanie A., Osterweil, Emily K., Bear, Mark F., Chattarji, Sumantra, Wood, Emma R., Wyllie, David J.A., Kind, Peter C.
Udgivet i Hum Mol Genet (2015)

Convergence of Hippocampal Pathophysiology in Syngap(+/−) and Fmr1(−/y) Mice

af Barnes, Stephanie A., Wijetunge, Lasani S., Jackson, Adam D., Katsanevaki, Danai, Osterweil, Emily K., Komiyama, Noboru H., Grant, Seth G.N., Bear, Mark F., Nägerl, U. Valentin, Kind, Peter C., Wyllie, David J.A.
Udgivet i J Neurosci (2015)

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

af Asiminas, Antonis, Jackson, Adam D., Louros, Susana R., Till, Sally M., Spano, Teresa, Dando, Owen, Bear, Mark F., Chattarji, Sumantra, Hardingham, Giles E., Osterweil, Emily K., Wyllie, David J. A., Wood, Emma R., Kind, Peter C.
Udgivet i Sci Transl Med (2019)

Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

af Hulme, Heather, Meikle, Lynsey M., Strittmatter, Nicole, van der Hooft, Justin J. J., Swales, John, Bragg, Ryan A., Villar, Victor H., Ormsby, Michael J., Barnes, Stephanie, Brown, Sheila L., Dexter, Alex, Kamat, Maya T., Komen, Jasper C., Walker, Daniel, Milling, Simon, Osterweil, Emily K., MacDonald, Andrew S., Schofield, Chris J., Tardito, Saverio, Bunch, Josephine, Douce, Gillian, Edgar, Julia M., Edrada-Ebel, RuAngelie, Goodwin, Richard J. A., Burchmore, Richard, Wall, Daniel M.
Udgivet i Sci Adv (2020)