Perturbed proteostasis in autism spectrum disorders

per Louros, Susana R., Osterweil, Emily K.
Publicat a J Neurochem (2016)

Myosin 1E interacts with synaptojanin-1 and dynamin via its SH3 domain

per Krendel, Mira, Osterweil, Emily K., Mooseker, Mark S.
Publicat 2007

Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model

per Muscas, Melania, Louros, Susana R., Osterweil, Emily K.
Publicat a eNeuro (2019)

Activation of mGluR5 Induces Rapid and Long-Lasting Protein Kinase D Phosphorylation in Hippocampal Neurons

per Krueger, Dilja D., Osterweil, Emily K., Bear, Mark F.
Publicat 2010

Mutations causing syndromic autism define an axis of synaptic pathophysiology

per Auerbach, Benjamin D., Osterweil, Emily K., Bear, Mark F.
Publicat 2011

A Differential Effect of Lovastatin versus Simvastatin in Neurodevelopmental Disorders

per Muscas, Melania, Seo, Sang S., Louros, Susana R., Osterweil, Emily K.
Publicat a eNeuro (2020)

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

per Osterweil, Emily K., Krueger, Dilja D., Reinhold, Kimberly, Bear, Mark F.
Publicat 2010

Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex

per Sidorov, Michael S., Kaplan, Eitan S., Osterweil, Emily K., Lindemann, Lothar, Bear, Mark F.
Publicat a Proc Natl Acad Sci U S A (2015)

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

per Krueger, Dilja D., Osterweil, Emily K., Chen, Stephanie P., Tye, Lynne D., Bear, Mark F.
Publicat 2011

Extinction of an instrumental response: A cognitive behavioral assay in Fmr1 knockout mice

per Sidorov, Michael S., Krueger, Dilja D., Taylor, Madison, Gisin, Eugenia, Osterweil, Emily K., Bear, Mark F.
Publicat 2014

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

per Lohith, Talakad G, Osterweil, Emily K, Fujita, Masahiro, Jenko, Kimberly J, Bear, Mark F, Innis, Robert B
Publicat 2013

Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome

per Tao, Jifang, Wu, Hao, Coronado, Amanda A., de Laittre, Elizabeth, Osterweil, Emily K., Zhang, Yi, Bear, Mark F.
Publicat a J Neurosci (2016)

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

per Osterweil, Emily K., Chuang, Shih-Chieh, Chubykin, Alexander A., Sidorov, Michael, Bianchi, Riccardo, Wong, Robert K. S., Bear, Mark F.
Publicat 2013

Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome

per Thomson, Sophie R., Seo, Sang S., Barnes, Stephanie A., Louros, Susana R., Muscas, Melania, Dando, Owen, Kirby, Caoimhe, Wyllie, David J.A., Hardingham, Giles E., Kind, Peter C., Osterweil, Emily K.
Publicat a Neuron (2017)

Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS

per Till, Sally M., Asiminas, Antonis, Jackson, Adam D., Katsanevaki, Danai, Barnes, Stephanie A., Osterweil, Emily K., Bear, Mark F., Chattarji, Sumantra, Wood, Emma R., Wyllie, David J.A., Kind, Peter C.
Publicat a Hum Mol Genet (2015)

Convergence of Hippocampal Pathophysiology in Syngap(+/−) and Fmr1(−/y) Mice

per Barnes, Stephanie A., Wijetunge, Lasani S., Jackson, Adam D., Katsanevaki, Danai, Osterweil, Emily K., Komiyama, Noboru H., Grant, Seth G.N., Bear, Mark F., Nägerl, U. Valentin, Kind, Peter C., Wyllie, David J.A.
Publicat a J Neurosci (2015)

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

per Asiminas, Antonis, Jackson, Adam D., Louros, Susana R., Till, Sally M., Spano, Teresa, Dando, Owen, Bear, Mark F., Chattarji, Sumantra, Hardingham, Giles E., Osterweil, Emily K., Wyllie, David J. A., Wood, Emma R., Kind, Peter C.
Publicat a Sci Transl Med (2019)

Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication

per Hulme, Heather, Meikle, Lynsey M., Strittmatter, Nicole, van der Hooft, Justin J. J., Swales, John, Bragg, Ryan A., Villar, Victor H., Ormsby, Michael J., Barnes, Stephanie, Brown, Sheila L., Dexter, Alex, Kamat, Maya T., Komen, Jasper C., Walker, Daniel, Milling, Simon, Osterweil, Emily K., MacDonald, Andrew S., Schofield, Chris J., Tardito, Saverio, Bunch, Josephine, Douce, Gillian, Edgar, Julia M., Edrada-Ebel, RuAngelie, Goodwin, Richard J. A., Burchmore, Richard, Wall, Daniel M.
Publicat a Sci Adv (2020)